Angry Toxicologist

Well, if MacGuire was talking about getting into toxicology research on plastics, he was right on. EHP has published a study showing that the additive BPA can cause cells to suppress adiponectin. That would cause insensitivity to insulin and may be behind “metabolic syndrome“. Let’s pause for a moment and think about that name. That’s got to be the worst name for a syndrome ever. It could only be more vague by being called ‘syndrome’. I prefer something that creates a nice visual, like bronchiolitis obliterans. Nothing like an obliterated lung to get your attention. I propose cardiolipoinsulinobesity disease. Hmmm…okay, we’ll stick with metabolic syndrome…or the slightly more technical, “F’ed up”. Seriously, it’s also called insulin resistance syndrome. It’s symptoms include obesity, heart disease, diabetes, general inflammation, prothrombic state (meaning you’re more likely to stroke out). Sweet.

It’s not clear how the BPA does this, though it’s likely due to it’s ability to disrupt hormones. In the study, estradiol (the potent estrogen) had the same effects on breast and abdominal fat tissue. They used human fat tissues that were removed from patients undergoing other procedures. The one issue I have here is that it may be that those undergoing the procedures have cells that react differently than the rest of the population. The samples came from patients getting breast reduction sugery, a tummy tuck, or gastric bypass. The people may have bodies that like to build up fat anyway, especially in the last two. Even if this is true, however, it at least means that some people are effected by BPA; in fact, it may be those who can least afford it.

There was a wide variety of effect of BPA (i.e. some patient’s tissues were sensitive to it and others weren’t). However, on average, BPA was more potent than estradiol at equimolar doses (that’s an equivalent dose based on the number of molecules, not weight, for those of you who didn’t take or don’t remember chemistry). Yikes!

Anyway, here’s the kicker. The levels were environmentally relevant. 1-10 nM are common in people (some up to 20 nM). The study found effects at 0.1 and 1.0 nM. Good ‘ole plastics. Is there anything they can’t do?

PS Here’s my water bottle advice.

Comments

  1. #1 Anna
    December 3, 2008

    Nice to see you back. :-)

  2. #2 NM
    December 4, 2008

    Welcome back.

    I was worried this place had died.

  3. #3 Anna
    December 8, 2008

    As soon as I traded in the plastic water bottles for stainless steel bottles, I read about potential nickel issues with stainless steel in water bottles, s/s cookware. Know anything about that?

    I’m not going to make any changes in my s/s usage yet, but I am keeping my ear to the rail to learn more about if nickel is a significant issue to consider or not. But if it’s like plastics, it will be another 20+ years at least before we’ll know, right?

    I’m not bothering with the new BPA-free plastics because who knows what the risks are of the new formulas.

    I’ve also traded out a lot of my plastic food storageware for tempered glass containers with silicon sealed leakproof plastic snap-top lids (I figure there’s generally less contact with the lid (greenlock by snapware is the brand). I really like these because they are rectangular, stack well, and make better use of angular cabinet and fridge space than round containers, are really clear and display the contents better ( the males in my household who suffer from “refrigerator blindness” are better at finding items now, sometimes even in the second row back), and are nice for serving at the table. I don’t reheat in the microwave much anymore, but microwaving can be done with these. But they are not approved for regular oven/range or toaster oven use.

    The only downside I’ve experienced is storing the empties – the small rectangular size nests into the medium size, but the medium doesn’t nest into the large (you’d think they could have managed a very slight dimension difference to accommodate that). So I nest the empty smalls in both of the empty larger sizes and stack them in a cupboard (though most of the time they are in use holding food). So far no breaks or chips, even with a clumsy 4th grader in the house and hard countertops. And I found them at both a big box houseware/kitchenware store (with 20% coupons but slightly higher regular prices) and at one of the local grocery stores near the food wrap section.

  4. #4 per
    December 21, 2008

    welcome back.

    so riddle me this; if BPA is potent on an equimolar basis with estrogen, surely you must accept that it cannot be acting through the estrogen receptors ?

    per

  5. #5 penis bytcler
    December 31, 2008

    penis bytcler

  6. #6 et
    January 1, 2009

    thanks you yess :)

  7. #7 sohbet
    January 1, 2009

    super sohbet etme yeri thankss

  8. #8 chat
    January 1, 2009

    thankss.

  9. #9 spor haberleri
    January 1, 2009

    gncel spor haberlerini bar?nd?ran sitedir..thankss.

  10. #10 sohbet
    January 1, 2009

    Thankss.Best regards..

  11. #11 Sohbet
    March 16, 2009

    very nice blog Thanks

  12. #12 sohbet
    March 16, 2009

    Thank you very much for this information.

  13. #13 muhabbet
    March 18, 2009

    Thx.

  14. #14 burun estetigi
    April 25, 2009

    The only downside I’ve experienced is storing the empties – the small rectangular size nests into the medium size, but the medium doesn’t nest into the large (you’d think they could have managed a very slight dimension difference to accommodate that).

  15. #15 konteyner
    May 18, 2009

    Thank you very much for this information…

  16. #16 kabin
    May 19, 2009

    Writes is very good thanks do you deserve to share:)

  17. #17 su deposu
    May 19, 2009

    I want to congratulate would follow ongoing blog, su deposu and really are very successful, thank you.

  18. #18 muhabbet
    May 26, 2009

    thank you.

  19. #19 paylasonline
    June 5, 2009

    Thank you very much for this information.

    http://www.islamodasi.net

  20. #20 islamisohbet
    June 6, 2009

    very nice blog Thanks

  21. #21 sohbet
    July 4, 2009

    thank you very much

  22. #22 yonja
    July 4, 2009

    ThankS.

  23. #23 accommodation wroclaw
    July 9, 2009

    It’s interesting… but is that true?

  24. #24 söve
    July 11, 2009

    The only söve downside I’ve experienced söve is storing the empties – the small rectangular söve size nests into the medium size, söve but the medium doesn’t nest söve into the large (you’d think they could söve have managed a very slight söve dimension difference to accommodate that).

  25. #25 sohbet
    July 20, 2009

    Here’s my question: isn’t any company free to charge any prices for its products, unless it’s a monopoly. Do the Big Four have a monopoly on music? If not, is charging Web stations and not charging terresrtial stations illegal? BTW, is it really true that terrestial stations pay nothing? That’s hard to believe.

  26. #26 sohbet
    July 20, 2009

    doesn’t nest söve into the large (you’d think they could söve have managed a very slight söve dimension difference to accommodate that).

    al? BTW, is it really true that terrestial stations pay nothing?

  27. #27 sohbet odaları
    August 20, 2009

    doesn’t nest söve into the large (you’d think they could söve have managed a very slight söve dimension difference to accommodate that).

    al? BTW, is it really true that terrestial stations pay nothing?…

  28. #28 chat
    August 24, 2009

    Very cool app. Can you tell me where to download the Help files? Apparently they didn’t make it during the install process, so it won’t load them. Thanks!

  29. #29 Forum
    September 15, 2009

    Thanks

  30. #30 kangallar
    September 20, 2009

    I am thanking for the knowledge

  31. #31 emlak
    September 30, 2009

    Thankjs..

  32. #32 anti cellulite cream
    October 31, 2009

    Really very interesting post.I was not knowing that plastic can also make us fat.

  33. #33 kangal
    November 9, 2009

    thanks very helpful

  34. #34 sohbet
    November 27, 2009

    It’s very useful for me. Thanks.

  35. #35 güzel sözler
    December 7, 2009

    It’s interesting… but is that true?

  36. #36 GENC
    December 10, 2009

    thnk youuuuu

  37. #37 uvip
    December 17, 2009

    I am behind you.You can count on it.

  38. #38 sohbet
    December 19, 2009

    Thank you very much for everything you share Mr. admin guys were good. good work.

  39. Thank you very much for everything you share Mr. admin guys were good. good work.

  40. #40 Driver Update Software
    December 31, 2009

    Plastics can make you fat? You are having a laugh ain’t you. Interesting post.

  41. #41 ev arkadaşı
    January 3, 2010

    thankyou admin for the info

  42. #42 Tummy Tuck Los Angeles
    January 9, 2010

    It’s all in the diet, lets not blame some plastic or something..

  43. want to congratulate would follow ongoing blog and really are very successful, thank you

  44. #44 Payday Loans
    January 18, 2010

    I completely that use of plastics is very harmful for our health. It adds harmful toxins in our body.

  45. #45 mapquest driving directions
    February 16, 2010

    Fantastic I hope you dont mind if I link to it from my wildfox couture vampire love website.

  46. #46 evden eve nakliyat
    March 3, 2010

    The only söve downside I’ve experienced söve is storing the empties – the small rectangular söve size nests into the medium size, söve but the medium doesn’t nest söve into the large (you’d think they could söve have managed a very slight söve dimension difference to accommodate that).

  47. #47 tatil
    September 22, 2010

    I also have a big contest coming up that I’d like to have all my affiliates involved in. I can understand not wanting to share it, but if you’re willing give me your email and I’ll send the info to you

  48. #48 tatil köyleri
    September 22, 2010

    Really looking forward to the next few days when people start properly aggregating this information. Will be interesting to see if what Google reports seem to match the studies we have done on the basis of your experiments for

  49. #49 eryaman hali yikama
    September 23, 2010

    I am behind you.You can count on it.

  50. #50 Fertility Treatments
    September 24, 2010

    Pregnancy time , mother not only take herself , she also take care in her baby. So that time she eat fresh fruit for health her baby and also self protection. For more information , Please visit http://www.pfcla.com/main/about-us/

    Thanking
    Fertility Treatments

  51. #51 konteyner
    October 6, 2010

    kekuatan platform blog yang dimungkinkan dengan software open source. Beberapa dari kita mungkin masih ingat bagaimana blog dulu tidak terlalu meledak ketika toolsnya masih proprietary dan/atau mahal dan/atau tidak terbuka. Kini ketika platform blog telah dibebaskan dengan berbagai software blog open source yang nyaman digunakan, maka kita semua yang meraup manfaatnya.

  52. #52 su_deposu
    November 9, 2010

    Themes. If you have any suggestions or changes please post a comment.
    Here is the ChangeLog for the Theme listing all the changes that I made compared to the original theme.
    http://www.sudeposu.eu

  53. Does plastic mean plastic surgery?
    i think if you beware everything you eat, nothing can make you fat.

  54. #54 konteyner
    November 24, 2010

    60 ülkede Karmod Karmod kalitesiyle bugüne gelindiginde 58 ülkede ürünü bulunan bir marka konumundadir. iklim kosulu olursa olsun farketmez. http://www.kartalprefabrik.com

  55. #55 Tonka Ricochet RC
    November 29, 2010

    i think it can’t make you fat but it can make globle warming

  56. #56 Hexbugs nano habitat
    December 1, 2010

    it can’t make you fat

  57. #57 jone
    December 6, 2010

    I am behind you.You can count on it.

  58. #58 西安二手房
    January 4, 2011

    think if you beware everything

  59. #59 tedavi
    January 19, 2011

    Vrea să păcălească milioane de suporteri” presa, cred ca de ea vorbeai, nu? ca altfel te crezi vreun sondaj, vreun barometru sau

  60. #60 tatil yerleri
    January 20, 2011

    Sorry to be such a pain here….but is Gol still showing the weekly hi-lite show? Thanks

  61. #61 Hexbugs nano habitat
    February 3, 2011

    how plastic make fat? i think it can’t make your body fat

  62. who linked to the post used the title as anchor text, and the post got more and more credibility in

  63. #63 cappadocia
    March 25, 2011

    Wow. I think this gets back to personal responsibility. The teacher should not have said what was said. The comment could have been made in a more authoritative tone. e.g. You should follow the dress code. The student should not have broken the rules and the mom should accept responsibility for raising her daughter improperly

  64. #64 Nakliyat
    April 19, 2011

    anlatım ve soyleyiş çok iyi

  65. #65 ginsengli bobo
    April 25, 2011

    who linked to the post used the title as anchor text, and the post got more and more credibility in

  66. #66 上海翻译公司
    May 7, 2011

    he student should not have broken the rules and the mom should accept responsibility f

  67. #67 güzel sözler
    May 29, 2011

    Really looking forward to the next few days when people start properly aggregating this information. Will be interesting to see if what Google reports seem to match the studies we have done on the basis of your experiments for

  68. #68 上海翻译公司
    June 26, 2011

    capture a date and time. I am currently using onSelect : function() { this.hide() } to close the popup when a date is selected. However this is not the best solution when a date a time is needed as people most often select the d

  69. #69 gunluk daire
    July 12, 2011

    This has made my day. I wish all psontgis were this good.

  70. #70 Favori Branda
    August 4, 2011

    Branda
    brandacı
    branda kumaş
    branda çeşitleri
    branda tente

  71. #71 alüminyum
    August 27, 2011

    capture a date and time. I am currently using onSelect : function() { this.hide() } to close the popup when a date is selected. However this is not the best solution when a date a time is needed as people most often select the

  72. #72 driver detective
    September 21, 2011

    Fat? I like fat and big people, like me!
    I am against this war against fat people

  73. #73 adana oto kiralama
    September 22, 2011

    Fat? I like fat and big people, like me. tahnk you for admin

  74. #74 Diyet
    November 11, 2011

    For the first time and I was amazed to hear,
    Thank you for writing.nice video:)

  75. #75 philosophy essays paper
    January 13, 2012

    Don’t you understand what real freedom is? At time you don’t compose your history essays, but essays writing service provides you with essays, you can see the autonomy.

  76. #76 guzel mesajlar
    May 3, 2012

    thank you