Like many advocates of science-based medicine, I was dismayed at the $200 million gift given by Susan and Henry Samueli to the University of California, Irvine in order to vastly expand its integrative medicine offerings. John Weeks, a noted promoter of integrative medicine, was not pleased at how the mainstream press covered this gift, and in particular he was most displeased that skeptics were heavily quoted in the reporting. In response, he launched a spittle-flecked, spelling-challenged broadside against his perceived enemies, full of misinformation and logical fallacies. Naturally, Orac can’t resist applying some not-so-Respectful Insolence to it.

A new analysis reveals that there are antivaccine bots on Twitter. Why am I not surprised?

Last week, I wrote about a truly execrable bit of science by Christopher Shaw and Lucija Tomljenovic purporting to show that aluminum adjuvants cause brain inflammation, which causes autism. Since then, I’ve learned that, not only is it bad science, but that there are red flags about several of the figures to raise the specter of fraud. This might not be just bad science. It might be fraudulent science. The only way to resolve this would be for the authors to release the original full resolution images of their blots.

Last week, UC-Irvine announced a $200 million gift from Susan and Henry Samueli to create a new integrative medicine center. Since then, UC-Irvine has tried to scrub any evidence of homeopathy use on its website. It didn’t work. Unfortunately, thanks to the Samuelis, homeopathy and other pseudoscience are deeply embedded in UC-Irvine, which has become the new epitome of quackademic medicine.

People with diabetes have less sRAGE

  When blood sugar concentrations are elevated, humans run the risk of glucose binding to proteins in the blood and causing the irreversible formation of advanced glycation end products (AGE). Once formed, AGEs can bind to their receptor (RAGE) and stimulate inflammation and oxidative stress. This pathological signaling can be stopped by pieces of the…

In yet another attempt to repeal and replace the Affordable Care Act, much of the GOP justification boils down to one argument: that the ACA isn’t working. Never mind that we don’t really know what constitutes a “working” health care system for Republicans.

Recently, the Hope4Cancer Institute, a quack clinic in Mexico has added a treatment known as Rigvir to its other offerings. But what is Rigvir? It turns out that it’s an import from Latvia with a mysterious history. Its proponents claim that it targets cancer specifically. Unfortunately, there is a profound paucity of evidence for its efficacy. The story of Rigvir is the story of an unproven treatment that, because of its origin in a small country, has flown mostly under the radar. Until now, that is.

Mexican tetra (Astyanax mexicanus) are a fascinating example of divergent evolution. Over time, some of these freshwater river fish washed into caves where they continue to live. With perpetual darkness, these cavefish have lost their ability to see along with their skin pigmentation. Oxygen and food are also hard to come by in the caves.…

Gwyneth Paltrow’s goop is continuing to sell snake oil promoted as the “empowerment” of women. Yes, that even includes a psychic vampire repellent, reiki charged.

Over the last couple of days I noted a disturbance in the antivaccine force, another study claimed to be slam dunk evidence that aluminum adjuvants in vaccines cause autism. It’s not. Also, a word to antivaxers challenging Orac to look at this study: Be very careful what you wish for…