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Corpus Callosum is written by a psychiatrist at a small community hospital somewhere in midwestern USA. Email to cc.scienceblogger at gmail dot com.


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« Two Views of Richat Structure | Main | Reversal of Progress on Folate Supplementation »

Drug For Fat Dogs

Category: CMEScience News
Posted on: January 6, 2007 3:47 PM, by Joseph j7uy5

The big Pharma news of the day is that Pzifer is marketing  (Slentrol®), a drug to help obese dogs lose weight.  

dirlotapide chemical structure

Dirlotapide, also known as N-{(1S)-2-[benzyl(methyl)amino]-
2-oxo-1-phenylethyl}-1-methyl-5-[4'-(trifluoromethyl)biphenyl-
2-carboxamido]-1H-indol-2-carboxamide, is definitely not recommended for humans:

Slentrol (dirlotapide) Goes to the Dogs
By Peggy Peck, Managing Editor, MedPage Today
January 05, 2007

ROCKVILLE, Md., Jan. 5 -- The FDA approved a diet drug today that it wants no one to even consider taking. Slentrol (dirlotapide), is an obesity agent for dogs, with nasty side effects if humans try it.

Slentrol, aimed at dogs that are at least 20% over ideal weight, will carry special warnings about its side effects when used by humans, starting with "not for use in humans."

The FDA also warned that humans who consume Slentrol may suffer abdominal distention, abdominal pain, diarrhea, flatulence, headache, nausea, and vomiting. [emphasis added]

Stephen Sundlof, D.V.M., Ph.D., director of FDA's Center for Veterinary Medicine, said Slentrol is a "welcome addition to animal therapies, because dog obesity appears to be increasing."...

Again, we see pharmaceutical companies producing something we don't really need.  

What we really need, is a drug for fat iguanas:

fat-iguana-500px.jpg


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Comments

OK, is it just me or does Drugs for Fat Dogs sound like a band name?

Posted by: NJ | January 6, 2007 4:56 PM

Actually that iggy's not fat at all. They carry their weight mostly in their tails, and to some degree in their hind legs. That one's too scrawny to be good eatin'.

(Obligatory disclaimer: I shared several years of my life with a couple of adopted/rescued adult male iguanas, and enjoyed their company quite a lot. I've never eaten iguana, nor do I intend to)

Posted by: Heidi | January 7, 2007 5:36 PM

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