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Corpus Callosum is written by a psychiatrist at a small community hospital somewhere in the USA. Email to cc.scienceblogger at gmail dot com.


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« Clostridium difficile Cases Increasing | Main

Oxytocin for Shyness

Category: NeurosciencePsychiatryScience News
Posted on: July 18, 2007 7:04 PM, by Joseph j7uy5

There is new information indicating that an nasal spray could be used to treat shyness.  Oxytocin is a peptide hormone best known for its role in childbirth and breastfeeding.  These are known as peripheral actions, meaning they take place outside of the central nervous system (CNS).

oxytocin.JPG

However, it also is known as a neurotransmitter, having effects within the CNS.  It has been touted as a chemical that can increase trust and reduce fear.  In fact, some companies have been marketing a perfume-like spray, which they claim a person can wear to affect the behavior of others.  That seems preposterous, but then, I haven't seen their data.

This new application has at least some data to support it...


, et. al., working at the , reports that it may work by affecting the amygdala.  This would have the effect of reducing the fear response.  This builds on prior work indicating that it reduces phobic fear, improves trust, and improves the ability to discern the emotional states of other people. The details of those studies can be found on his web page, linked above.

The study about the use in shyness have been reported in the media (New Scientist, Coolest Gadgets).  Apparently the original media report came from , as reported by Yahoo.  Reportedly, the results are to be formally presented at the International Brain Research Organization's World Congress of Neuroscience in Melbourne, Australia this week.  

A quick Medline search indicates that the results are not in print yet.  That being the case, it is difficult to make informed comments on whatever data he may have.  The media reports indicate that a commercial pharmaceutical product may be available in a little as five years.

Presumably, it would be intended as a treatment for .  If it really is safe and effective, it would be a welcome advance.  Currently the best drugs for Social Phobia are the .   can be used as well.  s can be used too, but frankly I have not been impressed by their efficacy.  There are problems will all of those approaches.  In fact, psychotherapy is probably the best treatment at this time.


  

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