Antidepressants

The Corpus Callosum

Category archives for Antidepressants

Antidepressant Effect of Vitamin D???

There is a thought-provoking editorial in the openly-accessible Journal of Psychiatry of Neuroscience (JPN): Has the time come for clinical trials on the antidepressant effect of vitamin D?  (45 KB PDF).  In it, the editor of the the Journal, Simon N. Young, PhD, argues that there is enough evidence to justify increased research efforts. He…

I haven’t gotten back to the “selection of antidepressants” series.  Mostly that is because, alphabetically, the next one is supposed to be citalopram.  While citalopram (Celexa™) is a perfectly fine antidepressant, it is kind of boring. So to spice things up a little bit, I’m going to jump ahead to desvenlafaxine.  This is a drug…

This is another post in a series detailing the selection of antidepressant medication.  Use the “Antidepressants” link in the “Categories” part of the sidebar to find the other posts in the series. In this post, I am sort of assuming that the reader has read the previous posts, or has an adequate fund of general…

This is an interesting drug.  Rarely prescribed, but interesting.  It is older than what we typically give today.  It is an antidepressant with a twist. In order to understand why it is interesting, you need to know a little bit about the pharmacology of the drug. Amoxapine is a tricyclic antidepressant, in my book, or…

This post is about amitriptyline, one of the oldest antidepressants on the market in the USA.  It also used to be the most widely-prescribed antidepressant. I’ve decided to not attempt an encyclopedic style of description of the pharmacological action of the individual antidepressants.  That is readily available already at Wikipedia, among others.  But in order to…

Selection of Antidepressants Pt. 5

A while back I started a series about the science and logic (and other factors) involved in the selection of antidepressant medication.  I suppose I could put in the pinks to the first four parts, but anyone can use the search box in the left-hand sidebar to search for “selection of antidepressants” to find them.…

Selection of Antidepressants, Pt. 4

Joltvolta (great name, by the way), asked a good question after I posted part 3. When you say proceed methodically, employ good data collection, etc. How does the individual do that for themselves? If they don’t have the availability to see a specialist multiple times a week, or even in a month, what options do…

Selection of Antidepressants, Pt. 3

It occurs to me that in order to go any farther explaining how to choose an antidepressant, I should take a moment to explain the concept of an adequate trial.  Earlier, I mentioned that the patient’s history of response to previous antidepressant trials is one of the most important factors to consider.  Having said that,…

Selection of Antidepressants, pt. 2

(Part One is here) Now we get to the heart of the matter: how does one decide what antidepressant to prescribe?  First, let’s take a look at the factors that are considered relevant to the choice.  If you understand what factors are relevant, and why they are relevant, then you will start to see how…

Many ScienceBloggers, and some science bloggers, are writing posts about basic concepts.  I thought that was a good idea, but could not think of one that would be interesting and that I felt like writing about and that I was particularly well-suited to write. Psychiatry is not a basic science.  It is a medical practice…