Neuroscience

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Category archives for Neuroscience

Zyprexa Adhera Nears Final Approval

Zyprexa Adhera is a new formulation of Eli LIlly’s antipsychotic medication, olanzapine.  It contains the same active ingredient as the pills, but it is a long-acting injection.  It is supposed to last two to four weeks. There is not a lot of specific information available yet.  It is not on the market yet, either.  The…

Several days ago, I saw an article about some research on the relationship between the price of wine, the subjective experience of taste, and the effect of wine on brain function as assessed by fMRI.   The research is part of the growing body of work that pertains to the study of neural effects of…

No Suicide Cringe

Usually I cringe when I see yet another newspaper article about suicide.  But I always read them.  This time, I did cringe, but needlessly.  The article turned out to be OK. F.D.A. Requiring Suicide Studies in Drug Trials By GARDINER HARRIS January 24, 2008

Sounds too good to be true.  Perhaps it is.  For one, there is only one published case.  For another, it has to be injected near the spine in order to have this effect.  The arthritis medication, etanercept (Enbrel®) has been shown, in at least one case, to result in significant cognitive improvement in a patient…

This cartoon was written before intranasal orexin was developed, but the same idea applies: Provigil (modafinil) is thought to act on the orexin system to promote wakefulness.  Indeed, it has attracted some attention due to its potential to increase productivity. Could the same effect — perhaps greater — be achieved with direct administration of orexin?

Roche Molecular Diagnostics offers a test that can determine which type of genes a person has for enzymes that metabolize antidepressant medication.  The test costs $ 300 to $400, and can be ordered by healthcare professionals, or by consumers. The idea is that it might be possible to predict which medications might be better for…

Brain MRI Animation

This is a brain MRI animation, showing sequential slices of the brain, from top to bottom.  It was a featured image at Wikipedia.   This was created by a Wikipedia user, Fastfission.  The explanation follows: Made from an fMRI scan I had done. Goes from the top of my brain straight through to the bottom.…

I haven’t gotten back to the “selection of antidepressants” series.  Mostly that is because, alphabetically, the next one is supposed to be citalopram.  While citalopram (Celexa™) is a perfectly fine antidepressant, it is kind of boring. So to spice things up a little bit, I’m going to jump ahead to desvenlafaxine.  This is a drug…

A great deal of evidence has accumulated that there is a problem with regulation of cortisol levels in persons with posttraumatic stress disorder.  Several years ago, it was demonstrated that adult offspring of persons with PTSD had lower circulating cortisol than others, and it appeared that the lower cortisol was a risk factor for the…

Using my new Firefox search box to search ScienceBlogs, I learned that Fetal Alcohol Syndrome (FAS) retards neural growth, screws up the circadian clock, is the subject of moralistic cartoons, and that it cannot be cured.   True enough, it cannot be cured.  Even so, it is important to recognize it, as early as possible, …