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The Corpus Callosum

The Corpus Callosum is an occasional journal of armchair musings, by a suburban, reality-based, slightly-left-of-center guy, who reserves the right to be highly irregular at times. Topics: social commentary, neuroscience, politics, science news. Mission: to develop connections between hard science and social science, using linear thinking and intuition; and to explore the relative merits of spontaneity vs. strategy.

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Corpus Callosum is written by a psychiatrist at a small community hospital somewhere in the USA. Email to cc.scienceblogger at gmail dot com.


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Psychiatry:

This Is Depressing

Category: Psychiatry

The standard wisdom in management of Major Depression, is that medication plus psychotherapy is better that either treatment alone.  Many studies have shown this.  But this one does not. Cognitive Behavioral Analysis System of Psychotherapy and Brief Supportive Psychotherapy for...

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Sexual Orientation Change Efforts Fruitless

Category: Psychiatry

In 2007, the American Psychological Association commissioned their Task Force on Appropriate Therapeutic Responses to Sexual Orientation.  The background is this: early in the history of mental health treatment efforts, homosexuality was considered to be an illness.  Therefore, it was...

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Are Randomized Controlled Trials Relevant?

Category: Psychiatry

This is from an open-access article in the Canadian Journal of Psychiatry: an article featuring a debate about the relevance of randomized, controlled trials to clinical practice.  It is mostly about research on psychotherapy, but with some treatment of psychopharmacology....

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Iloperidone, Approved For Treatment Of Schizophrenia

Category: Psychiatry

The new drug is called iloperidone; the brand name in the USA will be Fanapt.  It is yet another antipsychotic that blocks D2 and 5HT2 receptors.  Although there is no universally accepted way of classifying drugs into families, it will...

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Poets On Prozac

Category: Psychiatry

Poets on Prozac is the short title of a book by psychiatrist-poet Richard M. Berlin, MD.  The full title is: Poets on Prozac: Mental Illness, Treatment, and the Creative Process.  Berlin was an associate professor of psychiatry at the University...

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Clozapine Augmentation with Lamotrigine

Category: Neuroscience

It is refreshing to see something like this.  Both drugs are available as generics, so the financial motivation for a study like this is not great.  But the clinical benefit could e substantial, albeit for a small subset of patients....

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Fatigue

Category: Medicine

I haven't been a good blog-citizen lately.  And no, it is not because of fatigue.  Anyway, I've going to try to get back to looking at other people's blogs more, and not just here at ScienceBlogs.  Dr. Serani kindly pointed...

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What Is Behavior?

Category: Psychiatry

Natalie Angier has another interesting article in the NYT.  In the article, she discusses the meaning of the word behavior.  Apparently, this all came from the realization that even standard works on the subject did not contain a "point-by-point definition." ...

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Why DSM-V Doesn't Worry Me

Category: Psychiatry

A friend sent me a link to an article about the upcoming fifth edition of the American Psychiatric Association's Diagnostic and Statistical Manual.  The article speaks of flaws in the process, and warning of dire "unintended consequences." A Warning Sign...

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Comparative Effectiveness Research: Priorities for Mental Health

Category: Medicine

Comparative Effectiveness Research (CER) has been controversial, as noted in the Washington Post.  Admittedly, most of the controversy has been contrived.  Fortunately, the process is moving forward; there is no meaningful opposition at this point. A good summary of the...

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