Now on ScienceBlogs: The Lights Stay On Inside a Black Hole!

Seed Media Group

Collective Imagination

« Mental Care for Veterans | Main | The Psychology of Blogging »

Hydrogen Peroxide Doesn't Work

Category: Culture
Posted on: June 19, 2007 10:19 AM, by Jonah Lehrer

It was one of those unquestioned rituals of childhood: after getting a little scrape or cut (generally in the knee or elbow area), your mother dutifully applies some hydrogen peroxide to the injury. The peroxide burns, but the pain is just evidence that the peroxide is working. The cut is being cleaned. That, at least, was my childhood understanding of bacterial theory. Only it turns out that hydrogen peroxide isn't useful at all. In fact, it may actually make things worse:

In a study published in The Journal of Family Practice in 1987, scientists compared the effects of various topical treatments by taking a group of volunteers, administering several small blister wounds on each of their forearms, and then infecting their wounds with bacteria. After applying a different treatment to each wound, they measured bacterial amounts and rates of healing. They found that hydrogen peroxide did not inhibit bacterial growth and that wounds treated with the antibiotic bacitracin healed far more quickly.

Another study, in The American Journal of Surgery, looked at more than 200 people who had appendectomies and found that hydrogen peroxide did not reduce the risk of infection at the site of their incisions.

How long before the empirical facts actually change our habits? My guess is that we won't stop applying hydrogen peroxide to minor cuts any time soon. The burn lets us pretend that we are doing something, and that's powerful medicine.

Share on: Stumbleupon Reddit Email + More

Trackbacks

Trackback URL for this entry: http://scienceblogs.com/mt/pings/43402

Comments (9)

1

The benefit of hydrogen peroxide is the bubbling, the creation of all that oxygen drives large things out of a deep wound. I would have suspected that it would not work on a small blister like the researchers used. I would use alcohol or anti-biotic cream on a shallow wound.

Posted by: KevinC | June 19, 2007 11:13 AM

2

I use hydrogen peroxide as a germicide on fresh fruits and vegetables.

It does a nice job of detecting where a citrus rind has began forming fungal spores, as it foams immediately even if the spot is too small for the naked eye to see.

I get 8 pounds of grapefruit a week from a farmers market for $2, and the hydrogen peroxide wash does minimize my losses due to fungus.

Posted by: Roy | June 19, 2007 11:26 AM

3

Interestingly, such things seem to be cultural. I grew up in the US, but have lived in France for the past two decades. It was common to put hydrogen peroxide on scrapes when I was a kid, but here they simply don't use it. They use "real" disinfectants (generally betadine, which contains iodine, and is what is used here in hospitals).

Posted by: kirkmc | June 19, 2007 12:03 PM

4

Never saw it used in the Netherlands either.
But I have been frequently smeared with iodine.

Posted by: robd | June 19, 2007 1:08 PM

5

Oddly enough, I've always wondered if such things as hydrogen peroxide don't do more harm than good. I mean, H2O2 is a very strong oxidizer -- shouldn't it contribute to cell breakdown of native tissue as well as foreign bacteria? (Besides which I have an uncle who is a chronic abuser of the stuff -- takes mouthfuls of it straight out of the bottle and uses it as mouthwash. I can't imagine making a regular habit of that is good for mucous tissue.)

Posted by: Brian X | June 19, 2007 1:23 PM

6

Brian X:


... I have an uncle who is a chronic abuser of the stuff -- takes mouthfuls of it straight out of the bottle and uses it as mouthwash.

I'm nearly certain I've seen H2O2 as mouthwash recommended on many an H2O2 bottle. It seems that in recent years the recommendation has been altered to include (further) dilution with water.

Posted by: llewelly | June 19, 2007 2:39 PM

7

Yes, hydrogen peroxide does kill a few cells when used for wound cleaning. However, the strong oxidation does kill anaerobe bacteria, especially tetanus, as well as bubbling dirt, debris and dead cells from the wound. It should only be used for initial cleaning, followed by TAO, betadine, or the like.

Posted by: chezjake | June 20, 2007 12:46 AM

8

H2O2 was not used for skin cleansing, but in diluted mixes to cleanse mucosal surfaces, ie, mouth / lips -- trying to remove clotted blood from injuries in these areas can do more damage.

Betadine / iodine is used on the intact skin surrounding the wound, not on the wound itself as betadine / iodine will destroy the subcutaneous / vascular cells that you need for internal wound repair.


Copious normal saline irrigation is best for cleansing a wound; betadine / iodine for the skin around the wound.

Some wounds should not be closed, but left open and packed with a saline gauze. The fine gauze should be packed into the wound cervices so the debris and dying tissue can be removed when the dressing is removed. The wound packing is usually wet to dry (but it can be moistened just before removal so that there is no further damage by pulling the away healthy tissue.)

The skin should be cleansed of the betadine / iodine and then covered with a dry dressing because the skin itself does not like to be wet for too long.

Most likely, more than you want to know...


When the 'non-painful' topical antibiotics came out, people were reluctant to use them because they did not 'sting' when applied and, hence, did not seem to be working!

Posted by: Elizabeth, MD, PhD | June 20, 2007 2:39 AM

9

H2O2 is used to control microbial activity in hydroponics systems.

Posted by: Obdulantist | June 21, 2007 12:37 PM

Post a Comment

(Email is required for authentication purposes only. On some blogs, comments are moderated for spam, so your comment may not appear immediately.)

ScienceBlogs

Search ScienceBlogs:

Go to:

Advertisement
Enter to win a free copy of The Monty Hall Problem
Visit the Collective Imagination blog
Advertisement
Collective Imagination

© 2006-2009 Seed Media Group LLC. ScienceBlogs is a registered trademark of Seed Media Group. All rights reserved.

Sites by Seed Media Group: Seed Media Group | ScienceBlogs | SEEDMAGAZINE.COM