Developing Intelligence

Archives for September, 2010

Sometimes, ground-breaking studies don’t get the attention they deserve – even from experts in the field. One great example of this is an elegant study by Nieuwenhuis et al. from CABN in 2003; in it, they conclusively demonstrate why a particular event-related potential – the negative-going frontocentral deflection at around 200ms following stimulus onset, aka…

Machines Learn How Brains Change

In last week’s Science, Dosenbach et al describe a set of sophisticated machine learning techniques they’ve used to predict age from the way that hemodynamics correlate both within and across various functional networks in the brain. As described over at the BungeLab Blog, and at Neuroskeptic, the classification is amazingly accurate, generalizes easily to two…

With our introduction to paired pulse transcranial magnetic stimulation (ppTMS) out of the way, we now turn to a 2010 PNAS paper by Neubert, Mars, Buch, Olivier & Rushworth in which conditioning TMS is applied to the right inferior frontal gyrus (rIFG) as well as the pre-supplementary motor area (pre-SMA) between 3 and 18ms prior…

Yesterday’s introduction to paired-pulse transcranial magnetic stimulation elicited an insightful comment from reader “Kix”: As you mention, TMS can be used in order to disrupt or to read out some areas of the brain. I don’t see why these functions should be mutually exclusive. For instance, delivering single pulse TMS over the primary motor cortex…

There’s a ton of super-interesting transcranial magnetic stimulation work coming out these days (e.g., here, here, here, here, here, and here) and much of it pertains to a very particular “paired-pulse” form of TMS (ppTMS). Before diving into the new work, I wanted a basic crash course on what we know (and what we don’t)…