I am a microbiologist and molecular biologist turned tenured biotech faculty turned bioinformatics scientist turned entrepreneur. My passion is developing instructional materials for 21st century biology (
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Dave Robinson and Joann Lau from Bellarmine College in Kentucky are going to be describing their student project in a free webinar next Friday, May 16th. Their students clone GAPDH (Glyceraldehyde 3-Phosphate Dehydrogenase) genes from new plants, assemble the DNA sequences, and submit them to the NCBI. Here's an example.
Plus, since GAPDH is a highly conserved, it's a great model for looking at evolution.
You can get more information and register here.
The cool thing about plants is that there's lots of material to work with.
Comments
What a fantastic idea!
Its easily extended to so many other areas of biology too - such as insects or fungi that can be easily found and has the potential to give students a real appreciation of how molecular genetics provides the best current proof of common descent.
Posted by: Sigmund | May 9, 2008 4:45 AM
The Circle Is Closed! When I was a grad student, a LONG time ago, as the exercise for a biochem lab class we purified and crystallized GAPDH. But we didn't solve the structure. :-) And there wasn't a PDB then anyway.
Posted by: Jan Miernyk | May 9, 2008 12:52 PM
You know, this sounds like it would be an interesting sort of way to do a metagenome. A single set of DNA distributed amongst several collaborators at different schools, teaching several microbiology classes, with 96 well plates split amongst several lab students.
Posted by: TomJoe | May 10, 2008 11:47 PM