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Genomics

Category archives for Genomics

It’s time for the annual blog about the annual Nucleic Acids Research (NAR) database issue. This is the 24th database issue for NAR and the seventh blog for @finchtalk. Like most years I have no idea what I’m going to write about until I start reading the new issue. Something always inspires me. This year’s…

On Sept. 30th, I’m going to be co-presenting a Bio-Link webinar on Genome Engineering with CRISPR-Cas9 with Dr. Thomas Tubon from Madison College.  If you’re interested, Register here.  Since my part will be to help our audience understand the basics of this system, I prepared a short tutorial with Molecule World .  Enjoy! A Quick CRISPR Tutorial…

Computers, biological data (molecular sequences, structures, and other data), websites, and databases are integral to modern research. Innovations like precision, or personalized medicine, expect a certain level of patient participation, and our future food and environmental sustainability will require that society can access a multitude of computer-based resources. Thus, higher education has an important role in…

Did you know small fragments of DNA are circulating in your blood stream? These short pieces of DNA are left behind after cells self-destruct. This self-destruction, or apoptosis, is a normal process. In the case of fetal development, certain cells in our hands die, leaving behind individual fingers. Immune system cells leave traces of DNA…

Bio Databases 2016

Someone missed the memo. Over the past year, news and presentations by NIH leaders like Philip Bourne have communicated that the proliferation biologically focused databases is unsustainable. However, unlike last year, where the number of databases tracked by Nucleic Acids Research (NAR) dropped by three databases, 2015’s net growth was 136. Counting databases is hard As summarized in…

“By night all cats are gray”  – Miguel Cervantes in Don Quixote   I’ve always liked Siamese cats.   Students do, too.  “Why Siamese cats wear masks” is always a favorite story in genetics class.  So, when I opened my January copy of The Science Teacher, I was thrilled to see an article on Siamese cat…

We’ve been fans of the Molecule of the Month series by David Goodsell, for many years. Not only is Dr. Goodsell a talented artist but he writes very clear descriptions of the ways molecules like proteins, RNA, and DNA work together and function inside a cell. To learn about proteins and their activities, I like…

National DNA Day has a fun challenge for teachers and classrooms using Pinterest.  Your class can join a larger, national, effort to create a National DNA Day Pinterest board by making your own class Pinterest board on DNA, genetics, and genomics.  Some possible topics are: Things to do with DNA DNA and health DNA and the Arts…

Bio Databases 2015

Something interesting happened in 2014. The total number of databases that Nucleic Acids Research (NAR) tracks dropped by three databases! What happened?  Did people quit making databases?  No.  This year, the “dead” databases (links no longer valid) outnumber the new ones. To celebrate Digital World Biology’s release of Molecule World I’ll discuss some of the new structure databases…

Sometimes when you go digging through the databases, you find unexpected things. When I was researching the previous posts on insulin structure and insulin evolution, I found something curious indeed.                     I wanted to find out how many different organisms made insulin, so I used a database…