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molecular structures

Category archives for molecular structures

but the red berries are RNA. Picture below the fold.

Want to learn more about Parkinson’s disease? See why a single nucleotide mutation messes up the function of a protein? I have a short activity that uses Cn3D (a molecular viewing program from the NCBI) to look at a protein that seems to be involved in a rare form of Parkinson’s disease and I could…

Lots of bloggers in the DNA network have been busy these past few days writing about Google’s co-founder Sergey Brin, his blog, his wife’s company (23andme), and his mutation in the LRRK2 gene. I was a little surprised to see that while other bloggers (here, here, here, and here) have been arguing about whether or…

Instead of enjoying a sunny summer day today, or partying with SciBlings in New York, I’m staring out my window watching the rain. Inspiration hit! What about searching for August? Folks, meet the HFQ protein from E. coli. I found this lovely molecule by doing a multi-database search at the NCBI with the term ‘August‘.

Over 2600 genetic diseases have been found where a change in a single gene is linked to the disease. One of the questions we might ask is how those mutations change the shape and possibly the function of a protein? If the structures of the mutant and wild type (normal) proteins have been solved, NCBI…

In the class that I’m teaching, we found that several PCR products, amplified from the 16S ribosomal RNA genes from bacterial isolates, contain a mixed base in one or more positions. We picked samples where the mixed bases were located in high quality regions of the sequence (Q >40), and determined that the mixed bases…

Meet the ribosomes

Ribosomes are molecular machines that build new proteins. This process of synthesizing a protein is also known as translation. Many antibiotics prevent translation by binding to ribosomal RNA. In the class that I’m teaching, we’re going to be looking at ribosome structures to see if the polymorphisms that we find in the sequences of 16S…

I love using molecular structures as teaching tools. They’re beautiful, they’re easy to obtain, and working with them is fun. But working with molecular structures as an educators can present some challenges. The biggest problem is that many of the articles describing the structures are not accessible, particularly those published by the ACS (American Chemical…

This morning I had a banana genome, an orange genome, two chicken genomes (haploid, of course), and some fried pig genome, on the side. Later today, I will consume genomes from different kinds of green plants and perhaps even a cow or fish genome. I probably drank a bit of coffee DNA too, but didn’t…

I added the spring colors.