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Discovering Biology in a Digital World

My thoughts on biology, teaching, life, and exploring the living world via the digital one. Only my opinions are represented by these postings, they do not represent the viewpoints of any funding agency or Geospiza, Inc.

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Sandra Porter I am a microbiologist and molecular biologist turned tenured biotech faculty turned bioinformatics scientist turned entrepreneur. My passion is developing instructional materials for 21st century biology (Geospiza Education).

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Learn about DNA with molecular models

Exploring DNA Structure


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  • The Tangled Bank
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    Cn3D:

    Comparing mutant and wild type structures

    How to compare mutant and normal protein structures.

    Mapping polymorphisms in 16S ribosomal RNA

    In the class that I'm teaching, we found that several PCR products, amplified from the 16S ribosomal RNA genes from bacterial isolates, contain a mixed base in one or more positions. We picked samples where the mixed bases were located in high quality regions of the sequence (Q >40), and determined that the mixed bases mostly likely come from different...

    How does a single nucleotide change make influenza virus resistant to a drug?

    Fun with molecular models!

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