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drug resistance

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Nick’s post on Amantadine resistance in swine flu was so interesting, I had to look at the protein structures myself. I couldn’t find any structures with the S31N mutation that Nick discussed, but I did find some structures with the M2 protein and Amantadine. Not only are these structures beautiful, but you can look at…

Two protein structures from an avian influenza virus are shown below. One form of the protein makes influenza virus resistant to Oseltamivir (Tamiflu®) Don’t worry, these proteins aren’t from H5N1, but they do come from a related influenza virus that also infects birds. technorati tags: molecular models, protein structures, influenza, bioinformatics, Cn3D