Clinical

Effect Measure

Category archives for Clinical

Abortion and the world that is

When CBS-TV decided to run an anti-abortion ad during the Superbowl there was a lot of talk about the propriety of airing highly polarizing advocacy advertising in such a highly visible media slot. There has been less talk about the content of the ad beyond the obvious fact it was making an implied argument against…

Thinking about abortion

I am pro-abortion. Not in the sense that I think abortions are good. I don’t. In the sense that I am pro-surgery for medical conditions that can be surgically treated, or pro-pharmaceuticals for medical conditions that can be treated with drugs. I consider an unwanted fertilization to be a medical condition with significant consequences that…

Hand sanitizer just right for doctors

I had to laugh when I saw FDA was warning consumers in Puerto Rico that some hand sanitizers had high levels of bacteria (Burkholderia cepacia) that can cause serious infections. It’s not really funny of course, except that one of the hand sanitizers was called ?MD Quality Hand Sanitizer? (the other one was “Bee-Shield Hand…

Statins: through a lens clearly

We’ve written quite a bit about statins because there is evidence that these plentiful and cheap drugs may be useful in treating or preventing the innate immune system’s catastrophic dysregulation sometimes called “cytokine storm” (see here, here, here, here, here for a few examples). A new study now suggests that daily statin use by people…

The dangers of weed

I know families that if you visited them and found them laughing, confused, dizzy, thirsty and vomiting and apparently hallucinating you would think, “everything’s normal.” On a July night in suburban Maryland, however, an after dinner social call by a relative didn’t think it was normal at all and EMTs were called and six adults…

Oral conception

Grant writing makes you crazy and also forces bloggers to stoop to ever lower levels. Hence this from the Discover Magazine blog via Boingboing. While trawling for gold in the medical case literature they struck it rich with the story of the 15 year old girl with no vagina who got pregnant by giving her…

Joint pain and migraines: weather or not

While I work on my monster grant proposal — I and my colleagues have been working on it for 9 months, but with the deadline only 3 months away it is time to turn the volume up to 11 — blogging may be light or brief. But posting something is an excuse to take a…

[Previous installments: here, here, here, here] We’d like to continue this series on randomized versus observational studies by discussing randomization, but upon reviewing comments and our previous post we decided to come at it from a slightly different direction. So we want to circle back and discuss counterfactuals a little more, clarifying and adapting some…

Continuing our discussion of causation and what it might mean (this is still a controverted question in philosophy and should be in science), let me address an issue brought up by David Rind in his discussion of our challenge. He discussed three cases where a rational person wouldn’t wait for an RCT before taking action,…

I’ve noticed that whenever I have the temerity to suggest (e.g., here and here) that maybe the word of the Cochrane Collaboration isn’t quite the “last word” on the subject and indeed might be seriously flowed, I hear from commenters and see on other sites quelle horreur reactions and implications this blogger doesn’t believe in…