Will add real comments and hopefully an mp3 tonight, but OMFG THIS WAS THE BEST DEBATE EVER!!! OMG!!! OMG!!! AAAAAAAAAAHAHAHAHAHAHA!!!!
AAAAAAAAAAAHAHAHAHAHAHA THE MP3! THE MP3, GUYS! START LISTENING AT THE 6:30 MINUTE MARK AAAAAAHAHAHAHAHAHA!!
Now updated below the fold!
This ‘debate’ was pretty much exactly what I expected. Having ‘debated’ Horowitz in the past, I wasnt surprised he completely dominated the conversation (LET ME FINISH! WILL YOU LET ME FINISH???). Aaand I figured there would be a bounty of crap, a cornucopia of crap, if you will, from ‘both sides’.
But I didnt think there would be so much crap! Its was like a DI conference where EVERYONE forgot to take their lithium! Such a crap bounty! So please, everyone, harvest as much crap as you want from this interview, and save it for a slow blag day when everyone needs a lol (Optimus Primate couldnt resist noming already).
I will take only the 3 questions posed to Horowitz and Duesberg. If you all have any lingering questions about the debate, though, or something they said about HIV, please dont hesitate to ask!
1. Is it possible that any virus could cause AIDS?
Yup! Viruses are only capable of infecting cells that have the right receptor on the outside. Just like herpes gets into your neurons or influenza gets into your lung cells, HIV-1 requires receptors that are only expressed on certain kinds of immune cells. Sometimes the virus stays quiet, and nothing really happens, but when lots of viruses are produced, the infected cells die. Some HIV Deniers say HIV-1 cant kill cells, but thats actually one of the red flags I use in my experiments– If I infect my cells, and 24 hours later they are all dead, I know I screwed up and added too much virus! I am not adding anything else to these cells (‘poppers’, AZT, etc) except HIV-1 viruses, and the CD4+ T-cells die.
But this doesnt have to be specific for HIV-1. Any virus that evolved the need to use CD4, or any other receptor on the surface of any other immune cell could infect and kill cells, leading to a form of immunodeficiency. So yes, ‘any’ virus could cause AIDS.
2. If HIV exists, what is its origin?
3. What are the effects of AZT?
What makes a REALLY good drug, whether its for HIV or something else, is a drug that ONLY effects the invader. For a good example, think of pennicillin! Unless you are allergic to it, humans can normally take pretty large doses of the drug to kill bacteria because humans dont have cell walls!
The problem with HIV-1 drugs is that retroviruses use a LOT of our cells machinery. You cant mess up HIV-1 without messing up a normal cellular process. BUT there are chinks in its armor! Entry inhibitors, reverse transcription inhibitors, integration inhibitors, maturation inhibitors (Im sure there are more I am forgetting)! AND the more chinks you attack at the same time, the harder it is for HIV-1 to evolve resistance to ALL of them at the same time, and remain as pathogenic.
Evolution as a medical therapy π