Yeah, that hasnt worked out too well for him.
Anyway, unlike Ivory Handed Creationists who dont lower themselves to doing anything as dirty as ‘research’, scientists have kept busy seeking out new proteins within our own bodies to explain some weird evolution in the Vpu gene of HIV-1. Turns out there is a component of the innate immune system that we didnt even know existed before we followed the trail of Vpus ‘unimpressive’ and ‘pathetic’ evolution– tetherin. Tetherin is a way all of your cells can defend themselves against retroviruses (or wayward ERVs). It prevents progeny viruses from spreading– they stay stuck to the infected cell. Neato!
Well, thats where we left those pathetic evilutionists desperately clinging to Darwinism three months ago. What have they done since?
Every so often, scientists get together at conferences to talk about their research. They can have colleagues critique what theyre doing, or help with new ideas on projects that have stalled. Conferences are like four straight days of concentrated geeky brainstorming.
My labmate just went to one of these at Cold Spring Harbor Laboratory.
And she got the lowdown on the latest in Vpu research for us!
One group looked at tetherin in non-humans (common, you didnt think tetherin is only found in humans cause were Specially Created :P), Rhesus macaques, African green monkeys, and mice. They knocked out Vpu in HIV, and tried to infect cell lines from those animals. Then they added Vpu back to see if the non-human tetherins could be wiped out with Vpu, like what happens in humans:
“These non-human tetherins are capable of restricting HIV-1 release, but in contrast to the human protein, are not overcome by Vpu expression, demonstrating the exquisite species specificity that is a common feature of retroviral restriction factors.”
HIV-1 Vpu is human tetherin specific!!!
Those worthless evilutionists are going so far as to put more research into the origins of tetherin!
Another group looked at the functional abilities of tetherin:
“… we examined its (Vpu) ability to inhibit the release of a variety of virions derived from retroviruses that share little sequence homology. These included: HIV-1, SIVmac, SIVagm, EIAV, MLV, HERV-K, and PFV. Tetherin appears capable of restricting the release of every retrovirus that we have tested thusfar.”
So Vpu is human tetherin specific, but human tetherin isnt HIV-1 specific. We didnt evolve this protein specifically in response to HIV-1…but HIV-1 sure evolved in response to us.
Very cool! Caint wait till these brainstorms get out into a publication!