Before I write this post, Im writing this major for realsies ‘notice’, because people have an amazing capacity to do stupid things:
The following study demonstrates how a component of green tea, EGCG, can help negate some factors involved in certain kinds of HIV-1 transmission.
This does not mean green tea stops HIV-1 transmission.
This does not mean that if you drink a ton of green tea, you cannot transmit to your partner.
This does not mean you can roll a green tea doobie, shove it up your vagaygay, and youre ‘protected’. Same for shoving a One-A-Day Weight Smart up your butt, or dipping your dick in Darjeeling.
Dont be a god damned idiot.
I love HIV-1 research. There is so much going on, there is so much to read about, so much to learn– I live in a small corner of HIV-1 research: evolution, fitness, HIV-1 population dynamics and such. I know a lot about my little research niche, but there has been cool stuff going on in other niches I had no idea was going on!
For example, mah mind was blown yesterday when I learned that there is a component of semen that enhances HIV-1 infectivity. Prostatic acid phosphatase. Bits of PAP stick together to form amyloid fibrils. These fibers stick to HIV-1, and then stick to target cells, thereby enhancing infectivity. You dont have to have purified, industrial PAP to see this effect– you can just mix sperm and HIV-1, throw it on target cells, and the virus infects more cells than when the sperms not there.
Well EGCG screws up the formation of other kinds of amyloid fibrils. They either keep the fibers from forming completely, or the proteins form little clumps instead of threads:
Bright idea: Maybe EGCG can negate the infectivity enhancing properties of PAP by screwing up fiber formation!
ATTENTION: Mixing EGCG with HIV-1 does nothing to stop HIV-1 infection. Figure 3A. NOTHING. EGCG DOES NOT STOP HIV-1 INFECTION!
What does happen, is that EGCG knocks HIV-1+PAP higher levels of infectivity down to (almost) HIV-1 only levels, Figure 3B. It (almost) gets rid of PAPs ability to enhance infection.
Which means that EGCG could be a cheap additive to microbicides and condoms, tipping the balance in our favor a little bit more. Still hasnt been tested in human trials, but this is some nice good news.