Archives for November, 2009

A long time ago, in a galaxy far far away, ‘visionary’ scientists like Francis Collins thought ‘genetic diseases’ were coming to an end. Because they believed in ‘OGOD’, ‘one gene, one disease’ (lol, *blink*), they were sure identifying ‘disease’ genes would… somehow… give us the ability to cure said diseases. Unfortunately, even ignoring the technical…

X-linked adrenoleukodystrophy (X-linked ALD) is a demyelination disease in little boys. The kids are usually dead before they hit adolescence. The demyelination mechanism is not the same as the demyelination disease you all have heard of, MS. With X-linked ALD, the kids dont have a functional ABCD1 gene. This means they cant break down very-long-chain…

Ongoing witch-hunt against Oklahoma scientists

Though only a handful of ERV readers are from Oklahoma, I know all of you are familiar with the handiwork of Senator Randy Brogdon. He was the fellow who recently tried to get Creationism taught in Oklahoma public schools (FAIL). Dude is a fucking IDiot (and just plain old idiot) who hates science: I am…

Professor Santiago Elena, one of the profs who presented at the Viral Evolution conference I went to last fall, is featured in a nifty video about watching evilution in action! Evolution of Life: Evolution before our eyes Just like I use evilution in the lab to understand the population dynamics of HIV-1 to create an…

Nef: Savior and Satan

Vpu has kinda been my accessory protein of choice here at ERV, but its not the only one with a super cool evolutionary history and super cool evolutionary implications. Another particularly fun one is Nef. This eeeeeeeety bitty HIV-1 protein (27 kDa) has a lot on its plate. Contrary to the ‘expert’ opinion of Michel…

Im going to be speaking about one of the many ways I use evilution in the lab– HIV-1 vaccine design! If youre around OU tomorrow, come check out as many talks as you can!