Archives for June, 2010

As Carl Zimmer recently (and rightly) pointed out at the end of an article on epigenetics, while the concept of being able to alter our epigenetic profiles for therapeutic purposes is a really attractive concept, our current epigenetic therapy options are very, very messy. Like I said last week: Lemme give you an example. Lets…

Rule #9284748 of Science

Rule #9284748 of Science: Your side projects will work beautifully, garnering you lots of middle-author yet high-end publications, while your main project stagnates in a puddle of its own filth, laughing maniacally as you poke it with a stick trying to get it to move. YAY SCIENCE!

FDA and NASA FTW! YAY!

HA! Know how Lenny is finally getting his comeuppance for selling all that quack crap? I got an anon comment this afternoon giving us a little update: Dear Mr. : This is to acknowledge receipt of your recent message left in my voice mail mailbox. We have opened a file on this matter and an…

Sex and junk

There is not really a good way to get rid of the junk in your genome. Pretty much, once its in there, its in there– there is no organized biochemical system that says “Oy! This ‘eres crap!” and cuts out the useless bits, cleaning up residual transposable elements like a chimney sweep. We just keep…

ERV junk in your junk

As if you all needed one more reason to want Junk DNA to stay JUNK, I just read a couple of neato papers on the impact of wayward ERV and LINE activity in testes/sperm development: MOV10L1 is necessary for protection of spermatocytes against retrotransposons by Piwi-interacting RNAs Mouse MOV10L1 associates with Piwi proteins and is…

ERVs adventures in DC

I had to go to Washington DC/Bethesda last week for a short conference. I spent almost the entire time pooping, thanks to some food poisoning I got from a very expensive, universally recommended restaurant. YAY!! Luckily I wasnt sick when Francis Collins was supposed to speak. But he had to cancel. Still pooping, btw. Awesome.…

HSV-1 and rhabdomyosarcoma update…

(previous post) Well shit. Shit. Goddammit.

Dog Whisperer: Most Aggressive Breeds

Our partners at NatGeo currently have a special episode of ‘The Dog Whisperer’ up on Hulu*– The Most Aggressive Breeds. 45 minutes and 59 seconds of me bawwwing. There are no bad dogs. Just bad owners. Reminded me of the UFC pitbull vs rottie/germie fight I had in my apartment this time last year (weenie…

XMRV and antiretrovirals

H/T to The Lay Scientist for getting my butt in gear to write this post. Imagine you arent feeling well. You go to the doctor, they run some tests, and it turns out you have a tumor. Well… your physicians arent sure if you have a tumor or not, but they sent some of your…

Summer undergrad induced diabeetus

Every summer, Bad Horse sends me a summer undergrad or two to brainwash ‘mentor during a summer research experience’. They start out as these cherub faced kids, and three months later, they are a step closer to getting their PhDs in Horribleness. Some labs dont have good luck with their students. Unmotivated, annoyed kids that…