The HIV+ fellow they treated for cancer with bone marrow from a deltaCCR5 donor is still alive and kicking 3.5 years later, and for all intents and purposes, ‘cured’ of HIV/AIDS.
They went through and immunologically characterized ‘The Berlin Patient’ and hes pretty much normal now. HIV+ patients lose the CD4+ T-cells in their gut mucosa pretty much right after acute infection. This guy has had his gut mucosa repopulated with T-cells from the transplant.
They cant find HIV-1 anywhere.
Anti-HIV-1 antibodies are decreasing (indicating a lack of current infection). Antibodies to Gag are totally gone (though they would pop up again, should infection rev up again. theyre pointless, non-neutralizing antibodies, but your body doesnt know that).
So, pop news is freaking out:
In the magazine, Hutter said he was a scientist “in the right place at the right time,” and “for me, it is important to have overthrown the dogma that HIV can never be cured.”
:-/ Well, I agree that Dr. Hutter was at the right place at the right time, I dont think it was dogma preventing anyone from doing what he did. It was him being at the right place at the right time…
Even though Brown’s procedure proved to be successful, Quinn warns this was a rare case and a bone marrow transplant is not a cure-all for other HIV patients.
“It is a near fatal procedure that he had to have done because of the leukemia, but this procedure is very expensive and you have to be transplanted with a donor who is shown to be already resistant to HIV,” Quinn said. “You’re asking for a tall order to replicate this in the future.”
Yup. Pretty much.
So, Ive got to conclude with the same thing I said two years ago:
Oh well. Its still cool. Appreciate it for being cool. But right now, with todays technologies, its not a solution to the worlds HIV-1 pandemic.