Because I am having so much fun at mah conference, I missed my chance to plug a Q&A ninja/journalist Trine Tsouderos hosted with Paul Offit, vaccine inventor.
Im sorry you all missed the chance to participate (Im hoping most ERV readers are Respectful Insolence readers, so you all got the info that way). I mean, Im having so much fun interacting with people working with HIV-1 vaccines right now, and I get all giddy nuts about that, and you all could have gotten a taste of it by having the chance to interact with Dr. Offit.
I sorry 🙁
So I there I was, minding my own business in Starbucks, taking a second to check up on what I missed, “LALALALALALALALA IM READING DR. OFFITS COMMENTS HASING SO MUCH FUN LALALALALALA… wait wat?”:
[Comment From Jamie Deckoff-Jones MDJamie Deckoff-Jones MD: ]
Are you concerned that the current epidemics of ME/CFS, ASD and GWI are related to vaccines? These neuroimmune disease cohorts are all of mysterious etiology and share many clinical similarities: sensory and cognitive processing deficits, susceptibility to and inability to clear certain infections, an unusual susceptibility to stress, increased oxidative stress, glutathione depletion, methylation blocks, mitochondrial defects, high levels of heavy metals, inflammatory bowel issues, hormone abnormalities and a suspicion that vaccines are implicated in pathogenesis. The pathology in humans is extremely similar to what is known of simple retroviral infections in animals. We have evidence that xenotropic and polytropic MuLVs are infecting humans (Lombardi et al Science Oct 2009, Lo et al PNAS Sept 2010). Given the history of the use of mouse and chick embryo cells for vaccine production coinciding with the history of Epidemic Neuromyasthenia (as documented by Henderson and Shelokov, NEJM 1959), the known presence of animal retroviruses in those cells, and the documented ability of these viruses to infect human cells, aren’t you the least bit concerned?
I was expecting to see The Usual Suspects in the anti-vax movement, but I wasnt expecting to see a XMRV kook… but I suppose it was an inevitable union. Actually, its starting to look like the union was, shall we say, ‘predestined’.
See, Dr. DJ started a blog a while back, chronicling her personal experimentation with recreational antiretrovirals. Apparently for a while she was convinced she had Chronic Lyme Disease and was psychologically addicted to antibiotics, and now shes moved on to harder stuff.
I was so disgusted by her behavior I felt a personal responsibility to put information about antiretrovirals and their use in treating real retroviral infections on the intrawebz:
Certain scientists have been particularly vocal against the use of antiretrovirals for XMRV. Scientists trying to tell doctors what to do. Why do they think that doctors or patients should care about their medical opinions? They need to do their work and stop trying to practice medicine. The real question is why do they care if patients try antiretrovirals for a retrovirus? Why wouldn’t they want to know if the drugs work?
*shrug* So, pretty clear that she has absolutely no understanding of why antiretrovirals are A Very Bad Idea, even if XMRV were unquestionably THE CAUSE of CFS. She doesnt want to know. She already Knows. So we are not dealing with a normal, rational human. We are dealing with a kook. A kook who is in a position of influence on a psychologically and physically vulnerable population, and is abusing that position of influence, which pisses me off. Because I am a lazy skeptic surrounded by critical thinking readers, I will now cease to interact with her on a rational level, and will now be quoting her for lulz:
Are we to believe this recombination event occurred only once and that a pathogenic MLV-related human retrovirus is only produced by one particular cell line? Told to us by some of the very scientists that said it was impossible? Anyone smell a cover-up? Much easier to destroy a seminal work than admit that there may in fact be a family of XMRVs. Careful reading of the Science paper shows that the monoclonal antibody used to detect XMRV envelope in Lombardi et al detects all known xenotropic, polytropic and ecotropic MLVs. Antibodies made by patients recognized specific envelope and gag proteins. PCRs were optimized for sensitivity, not specificity. And quite possibly there are many other recombinant animal retroviruses infecting humans as well, created in laboratories and injected into almost everybody in the industrialized world, because of arrogance.
Putting it all together, it seems quite plausible that batches of vaccines containing retroviruses that are infectious to humans have been going out for over half a century. Much of what I’ve written here has been known but ignored for a long time. The assumption was made that endogenous animal retroviruses couldn’t harm people. It’s becoming clear that this was a very incorrect assumption.
It is an old discussion, one in which the autism community has been embroiled for a long time. But the scientific community has chosen to believe that all those mothers of autistic kids are deluded, and don’t really know how or when their kids got sick. That they had normal kids and, within a few days of a vaccination were never the same, is just coincidence.
The press has been calling me recently. Why are vaccines such a hot potato? The big response to the subject exposes it as a sacred cow. What’s so controversial about a doctor saying that there is a chance that an unnecessary intervention may be harming patients and that, until we know more, the intervention should be held for people at risk? The automaticity with which doctors have come to prescribe vaccines is medically incorrect. We need to look at where we are now, not where we were when we started vaccinating Polio, Small Pox or Diphtheria. At this juncture, in my opinion, each vaccination should be thought about by a physician, in the same way prescribing a drug is. You don’t give drugs in batches to everyone. You consider each prescription carefully, for that patient, at that moment. That’s what is expected for every other prescription. Why should physicians suspend disbelief for this one therapeutic modality? A doctor is not supposed to hurt anybody, except that if he hurts somebody with a vaccination, that’s OK? Even if he already knows that this person has an immune dysfunction that hasn’t been studied with respect to vaccines? The patient has to live with the damage forever. Something is really wrong here. Doctors should think about that individual patient before ordering the shot. It shouldn’t be automatic if the patient has a history of CFS. What is the risk of worsening the disease from the shot? Or causing it in a family member? Risk to the individual, not the society.
The question. Did the conditions exist for the current epidemic of neuroimmune diseases to be the result of endogenous retroviruses present in animal tissues and used in the production of vaccines?
Cover-up or stupidity? I’m just a dumb ER doc and I’ve gotten this far with PubMed and a few scientist friends (who if asked will deny knowing me:). Though any detail of what I’ve written could be mistaken, and there is conflicting evidence, overall, it certainly seems to fit. People have written that they are concerned that I’m too invested in XMRV. This is not all about XMRV. If they prove tomorrow beyond a shadow of a doubt that XMRV is a lab contaminant and not present in humans, it doesn’t change a thing in terms of what needs to happen next. At the very least XMRV has brought attention to an international disgrace. If XMRV is buried under a mountain of negative studies, or if XMRV is truly not a human pathogen, millions of people still need treatment for neuroimmune illnesses that are consistent with simple retroviral infection.
The current epidemic of neuroimmune illnesses may be due to the introduction of simple retroviruses into the human population through the use of vaccines.
Yeah, Im totally lazy. Im just going to let those thousands of cuckoo bananas speak for themselves.
Its obvious to even the most casual observer that Dr. DJ is anti-vax, the way Lenny is an HIV Denier. She might not refute the utility of vaccination (I havent gotten the impression DJ understands how vaccines work or why we use them, so she hasnt delved into the science or epidemiological side of things), but she does have a laundry list of insane conspiracy theories. Likewise Lenny doesnt necessarily deny HIV-1 causes AIDS, but he thinks its creation was a government conspiracy.
If I were a legitimate scientific organization, I would not want to be associated with her in any way, shape, or form. I wouldnt even friend her on Facebook, for fear her insanity would taint my reputation.
Hey, speaking of Facebook!
Thanks to her completely self-unaware comment on Trines site and zero internet skillz, I saw on her Facebook page that she ‘likes’ an anti-vax group, ‘Autism Mothers’. ‘Autism Moms’ advertises for BioRay. BioRay is buddy-buddy with Mikovits and the WPI. Mikovits took time out of her busy research schedule to speak with Andrew Wakefield and Jenny McCarthy at AutismOne, while WPI is run by the Whittemores, a couple of folks who let their daughter pass up MMR (which youre supposed to get as a toddler) until she was 17, who now blames her ‘relapse’ of ‘CFS’ after she was ‘cured’ by ‘yoga and homeopathy’ on the MMR. The WPI, a ‘legitimate scientific organization’ just hired Dr. DJ.
WHAT A CRAZY RANDOM HAPPENSTANCE!
WEIRD COINCIDENCES, HUH GUISE?