One problem we have to deal with in HIV-1 world (of the many problems we have to deal with) is that no one is ‘cured’ of HIV/AIDS (except this guy).
So people who are infected go on to infect more people, who go on to infect more people, who go on to infect more people… I mean thats how we *got* a pandemic.
So since we cant get rid of HIV-1 once it has infected someone, it means the trick to stopping the pandemic is to stop new infections. Interrupt the dominoes falling, protect the down-stream dominoes.
We have a way of doing that: condoms.
But for any number of reasons, condoms are not always used, so transmissions continue.
So thats why I am working on an HIV-1 vaccine. You might not wear a condom all the time (by choice, or by situation), but your antibodies and CTLs will still be there to protect you if youve gotten an anti-HIV vaccine.
… In case you havent noticed, we are having some difficulty making an efficacious HIV-1 vaccine… *blink*
So other people are exploring other ways to prevent new HIV-1 infections. One idea– using the anti-HIV drug tenofovir as a once-daily medication or as a component in microbicide to prevent new HIV infections (analogous to The Pill and spermicides for preventing pregnancy). Initial studies looked promising!
* 6.1% in the inactive placebo gel group acquired HIV in a twelve-month period
* 6% in the tenofovir gel group acquired HIV in a twelve-month period
The best we can hope to get out of this, is to figure out why tenfovir did not work in either form in this study, and hopefully we can figure out how to fix it.