Cancer

Category archives for Cancer

This is one of the cool ideas not included in the 1800 human gene therapy trials because its still in animal models, not humans: Preclinical Therapy of Disseminated HER-2+ Ovarian and Breast Carcinomas with a HER-2-Retargeted Oncolytic Herpesvirus If Ive said it once, Ive said it 1000 times: ‘Cancer’ is not a monolithic entity. We…

Hold off on the chemo! Herpes doesnt like it!

Hey remember how I told you all scientists are using herpes, the regular-ol much hated cold-sore virus, to treat/cure cancers? The approach has left us with miraculous effects… or no effects at all. I mean, half of the melanoma patients lived A LOT LONGER than they were supposed to, several of them ending up with…

A lot of folks have been forwarding me this story from the New York Times–  In Girl’s Last Hope, Altered Immune Cells Beat Leukemia It is a FANTASTIC story about a little girl who had been sick from leukemia for two years, wasnt responding to conventional therapies, and her parents chose to try alternative medicine. …

Scientists all around the world are creating legions of genetically modified viruses to treat/cure human afflictions, from nicotine addiction to hemophilia (A and B). One disease a lot of folks are focused on in brain cancer.  Certainly not a monolithic entity– but scientists are working on viruses against them all.  One of the viruses on…

NICE! Gene therapy of pancreatic cancer targeting the K-Ras oncogene Cancer sucks, but some kinds of cancers suck worse than others.  One that really sucks is pancreatic cancer.  From the intro of this paper: Pancreatic cancer (PC) is the fourth leading cause of cancer death among men and women, comprising 6% of all cancer-related death.…

GMO HSV-1 vs Brain Cancer

Orac wrote yesterday about the abominable union between anti-vaxers and anti-GMOers: “Genetically modified” vaccines and GMOs: Sapping and impurifying all our precious bodily fluids? My ‘message’ to these kinds of people?  Get over it.  Fast.  Because you look ridiculous. Skinner: Im telling you people, the earth revolves around the sun! Abe: Burn him! [lights the…

Madness? THIS IS SCIENCE!!!!!!!!!!!

Science hath no insanity like the XMRV fiasco. *sigh* But there is a constant, bright spot in this ridiculous storm, and I dont want it to be overlooked– The scientific leadership of Robert Silverman, and everyone associated/partnered with his laboratory*. As a young, hopeful, yet increasingly derisive scientist like myself, Silvermans behavior throughout all of…

ERVs and Multiple Sclerosis, #5

This is not overly helpful information for MS patients, but its still good news: No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients. Previous research has indicated that there are endogenous retroviruses that are disregulated and leading to detectable production of ERV proteins in MS patients.  They found the bugger involved–…

GMO Herpes vs severe cancer pain

What happens when the pain gets to be too much?  What happens when the drugs stop working?  The physicians are giving you as much as you can take without dying, and youre still living with 7, 8, 9 levels of pain, every waking moment?  Some of the talk behind physician assisted suicide is to let…

Look, scientists are nuts.  Virologists, on the other hand, are certifiably insane.  As Hedwig would say, virologists make the strangest things seem suddenly routine.  Yesterdays absurd future technology (GENE THERAPY!) is now something as miraculous as curing genetic diseases, and as mundane as an anti-smoking therapy. Todays insane idea? Using mouse and rat parvoviruses to…