Cancer

Category archives for Cancer

NICE! Gene therapy of pancreatic cancer targeting the K-Ras oncogene Cancer sucks, but some kinds of cancers suck worse than others.  One that really sucks is pancreatic cancer.  From the intro of this paper: Pancreatic cancer (PC) is the fourth leading cause of cancer death among men and women, comprising 6% of all cancer-related death.…

GMO HSV-1 vs Brain Cancer

Orac wrote yesterday about the abominable union between anti-vaxers and anti-GMOers: “Genetically modified” vaccines and GMOs: Sapping and impurifying all our precious bodily fluids? My ‘message’ to these kinds of people?  Get over it.  Fast.  Because you look ridiculous. Skinner: Im telling you people, the earth revolves around the sun! Abe: Burn him! [lights the…

Madness? THIS IS SCIENCE!!!!!!!!!!!

Science hath no insanity like the XMRV fiasco. *sigh* But there is a constant, bright spot in this ridiculous storm, and I dont want it to be overlooked– The scientific leadership of Robert Silverman, and everyone associated/partnered with his laboratory*. As a young, hopeful, yet increasingly derisive scientist like myself, Silvermans behavior throughout all of…

ERVs and Multiple Sclerosis, #5

This is not overly helpful information for MS patients, but its still good news: No additional copies of HERV-Fc1 in the germ line of multiple sclerosis patients. Previous research has indicated that there are endogenous retroviruses that are disregulated and leading to detectable production of ERV proteins in MS patients.  They found the bugger involved–…

GMO Herpes vs severe cancer pain

What happens when the pain gets to be too much?  What happens when the drugs stop working?  The physicians are giving you as much as you can take without dying, and youre still living with 7, 8, 9 levels of pain, every waking moment?  Some of the talk behind physician assisted suicide is to let…

Look, scientists are nuts.  Virologists, on the other hand, are certifiably insane.  As Hedwig would say, virologists make the strangest things seem suddenly routine.  Yesterdays absurd future technology (GENE THERAPY!) is now something as miraculous as curing genetic diseases, and as mundane as an anti-smoking therapy. Todays insane idea? Using mouse and rat parvoviruses to…

If you are reading this blog, you already know all about how a huge portion of your genome is parasitic junk DNA (~40-45%), a fraction of which is retroviral junk (ERVs, ~9%).  If youre new here… SURPRISE! Sure, we have a gene here, a promoter there (maybe) that was domesticated for human genome use, but…

Common everybody! Sing the chorus with me, you know the words! The vast, vast majority of ERVs are junk. They are genomic pirates, and your genome is doing the best it can to keep them silent. When ERVs are making noise, its a sign that something has gone wrong. Very, very wrong. Like, for example,…

Why havent we cured cancer yeeeeeeeeet?

Last time I talked about why treating cancer is so hard: Why havent we cured cancer yeeeeeet? Briefly, scientists did complete genome sequencing of seven individuals prostate tumors, and things were all kinds of jacked up. Not only were all seven tumors different, but one tumor had over 200 chromosomal rearrangements. Like taking your genome…

MMTV and Breast Cancer

Sorry, Hitch. Religion doesnt poison *everything*. Thanks to the bumbling efforts of ‘respected’ scientists like Judy Mikoivts, we now know that its not religion, but mouse DNA, that poisons everything. Relatively new readers of ERV are well aware of the fact that all efforts to connect XMRV to any human pathogen have ended up being…