Epigenetics

Category archives for Epigenetics

New ideas for saving Tasmanian Devils

I cannot deal with the fact Tasmanian Devils are being driven to extinction by a contagious, untreatable cancer. I cannot deal with it. Click on the first link to see the science behind the tragedy: Numbers arent enough Click on the second link to see why I cannot deal with this, psychologically: Oh no… Cedric…

*sigh* *heaviersigh* One of the many problems we have when treating HIV patients is that HIV can hide (latent). So a cell can be infected with HIV, but not show any signs of being infected. The HIV provirus is just chillin in the host cell DNA, not making any viral proteins/babby viruses, so the individuals…

ERVs, epigenetics, and the alcoholic brain

Let me make this clear, for like the millionth time: You do not want transposable elements in your genome (DNA transposons, ERVs, LINEs, SINEs, etc) to be active and functional. You are happy, happy, happy that these elements are junk. Yes, occasionally a transposable element has been domesticated for the hosts purposes. Yes, I know,…

HERVs and HIV-1

Quick recap of ERVs for new readers of ERV (or long-time readers who have forgotten!)– ERVs are retroviruses that accidentally infected an egg/sperm cell, and became a permanent part of that egg/sperms DNA. That egg/sperm then went on to successfully generate a viable embryo, and because that retrovirus was part of the egg/sperms DNA, it…

HuffPo lulz

If there is one thing that terrifies me as a blogger, its noticing site-hits from HuffPo. It means one of two things– 1– They stole some of your content 2– One of their kook ‘writers’ linked to you, and a shitstorm of crazy is about to invade Yeah… I noticed some hits from HuffPo yesterday……

A long time ago, I think on Pharyngula, Richard Dawkins said something that really pissed me off. Its been so long ago I cant find the right comment thread anymore, but Dawkins said something regarding epigenetics along the lines of “Um… isnt this just a fancy word for transcription regulation? Stuff weve been studying for…

As Carl Zimmer recently (and rightly) pointed out at the end of an article on epigenetics, while the concept of being able to alter our epigenetic profiles for therapeutic purposes is a really attractive concept, our current epigenetic therapy options are very, very messy. Like I said last week: Lemme give you an example. Lets…

ERVs adventures in DC

I had to go to Washington DC/Bethesda last week for a short conference. I spent almost the entire time pooping, thanks to some food poisoning I got from a very expensive, universally recommended restaurant. YAY!! Luckily I wasnt sick when Francis Collins was supposed to speak. But he had to cancel. Still pooping, btw. Awesome.…

KLZF KRABs with nine zinc fingers…

Okay, you know how I say with ERVs and disease: Expression of the ERV protein causes the disease Expression of the ERV is an effect of the disease (a useful biomarker) Expression of the ERV is an effect that perpetuates the disease I just read a paper that exemplifies #3! Regulation of human endogenous retrovirus-K…

Epigenetics is not magic.

My god, epigenetics is a woo-magnet. Its not epigenetics fault, its just science. But the word ‘epigenetics’ gets put on this (‘chambery thing’ heh.). And this. And this. And… well, just Google it. Find your own favorite bit of self-help/explain all/magic epigenetic crap. Attention woo-meisters: STOP WHORING UP EPIGENETICS. IT IS NOT MAGIC. ITS JUST…