Vaccines

Category archives for Vaccines

The Evolutionary Consequences of Blood-Stage Vaccination on the Rodent Malaria Plasmodium chabaudi The concept of vaccination is, superficially, simple– Safely mimic ‘infection’ so your immune system learns how to fight a pathogen, without needing to get sick from the genuine pathogen.  Then if you are ever exposed to the real, scary pathogen, your immune system…

Briefly, a lot of our vaccines and antibiotics need to be refrigerated, if not frozen, for them to maintain their usefulness. This makes it problematic to get vaccines and antibiotics to places that need them, but lack proper refrigeration (or electricity, for that matter)– Its called the Cold Chain. Some folks at Tufts think they…

HPV and head/neck/throat cancer

The ‘debate’ over the HPV vaccine has thus far has been a tug-of-war with radical religion/conservative politicians/nutbar anti-vaxers on one side, and the lives of women on the other side. The HPV vaccine has been A Female Issue. Turns out the people opposing the HPV vaccine were damning male children, as well. Though I wrote…

Herd Immunity In Action: HPV Vaccine

Herd immunity– If a lot of people are protected from a pathogen then the people who arent protected, are still protected.  The higher the percentage of ‘protected’ people, the better herd immunity works. Here is a simple animation of how herd immunity works. While we generally think of herd immunity as it relates to the…

File this under “Cool, but not the best experimental design and maybe a bad idea in humans (but maybe a good idea under some circumstances)”– Effects of Novel Vaccines on Weight Loss in Diet-Induced-Obese (DIO) Mice, pdf: www.jasbsci.com/content/pdf/2049-1891-3-21.pdf Somatostatin is part of several chemical pathways in your body– one of them is the inhibition of…

If you are reading this blog, you already know all about how a huge portion of your genome is parasitic junk DNA (~40-45%), a fraction of which is retroviral junk (ERVs, ~9%).  If youre new here… SURPRISE! Sure, we have a gene here, a promoter there (maybe) that was domesticated for human genome use, but…

File this under ‘Religion has nothing to do with morality’– Some religions have a problem with a vaccine that, when dosed appropriately early enough, virtually eliminates risk of cervical cancer, as virtually all cervical cancer is caused by HPV.  Its even better if males get the vaccine as well, not only because if fewer males…

I have no idea how I missed this insane bit of news last year:  The CIA organised a fake vaccination programme in the town where it believed Osama bin Laden was hiding in an elaborate attempt to obtain DNA from the fugitive al-Qaida leader’s family, a Guardian investigation has found. As part of extensive preparations…

Epic disaster in HIV vaccine world

I can think of at least two ‘worst nightmares’ for vaccine designers. Your vaccine looked super in animal models and such… but it turns out to be directly harmful to people.  And not ‘some’ people.  All people. Your vaccine actually does the opposite of what you want it to do– instead of preventing the disease,…

ERV at Skeptics of Oz

HAAAAAAHAHAHAHAHAHA!  I feel like Stewie Griffin. I DONT LIKE CHANGE!!! Give us a minute, we will figure it out (hey, I figured how to get pages of comments so Our Epic Threads dont take over 9000 years to load! dont have to top it off at 5K!!!) In the mean time, Skeptics of Oz have…