Cancer

Tag archives for Cancer

Five kids in the first trial. Then eleven. Now thirty (ultimately 39): Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia Slowly but surely, HIV genetically modified to genetically modify relapsed acute lymphoblastic leukemia (ALL) patients T-cells are prolonging (saving?) kids lives. Ive written about this treatment a couple times before: ‘Dismal prognosis’ with…

GMO Vaccine-Strain Measles vs Cancer

So scientists cured a woman of a pervasive, treatment resistant multiple myeloma. With a genetically modified, vaccine strain measles virus. Remission of Disseminated Cancer After Systemic Oncolytic Virotherapy *anti-vax-anti-GMOers-heads-explode* The media is going nuts over this, but this is not a new idea/approach. Measles, and certain other viruses, can be domesticated and modified to kill cancers–…

WHY IS THIS NOT STANDARD THERAPY YET? Efficacy and Toxicity Management of 19-28z CAR T Cell Therapy in B Cell Acute Lymphoblastic Leukemia I wrote about this last year: ‘Dismal prognosis’ with leukemia? Nothing a GMO virus cant fix. In the previous study, scientists took cytotoxic T-cells from five B-ALL patients, and infected them with…

Michael Douglas and HPV

Michael Douglass recently announced that his battle with throat cancer was instigated by HPV. We have known for a long time that males can benefit from the HPV vaccine series. I wrote this back in 2011: CDC recommends HPV vaccine for boys! It would be great, for women, if boys got the vaccine too. Of…

New ideas for saving Tasmanian Devils

I cannot deal with the fact Tasmanian Devils are being driven to extinction by a contagious, untreatable cancer. I cannot deal with it. Click on the first link to see the science behind the tragedy: Numbers arent enough Click on the second link to see why I cannot deal with this, psychologically: Oh no… Cedric…

Using a genetically modified HIV-1 to genetically modify leukemia patients T-cells to teach them how to kill the cancer? YAWN! Thats childs play, at this point. Lets give those GMO viruses a real challenge. Lets get them to fight a real bastard form of leukemia– B-cell Acute Lymphoblastic Leukemia (B-ALL) in adults. In kids, B-ALL…

Another day, another disease treatment strategy based off a genetically modified virus! Prostate Specific Antigen Retargeted Recombinant Newcastle Disease Virus for Prostate Cancer Virotherapy. This one is so clever, you guys. It is so freaking clever! Some of you might know that sometimes, when prostate cancer is present, there is an elevated level of ‘Prostate…

Here is a nice open access review article on ERVs and their association with cancer: Human endogenous retroviruses and cancer prevention: evidence and prospects While thats wonderfully interesting, what I want to focus on is a bit at the end. More information I have never heard before– An amino acid sequence similar to HERV-K-MEL, recognized…

ERMAHGERD! ERVALANCH! ERVs and melanoma

I was actually unaware of this– But melanoma is Yet Another Disease that has been associated with wayward ERV transcription and translation.  Scientists have found inappropriate ERV RNA, protein, and anti-ERV antibodies in melanoma patients. This is the first paper to break down ‘melanoma’ into subtypes (like ‘cancer’ is not monolithic, all ‘melanomas’ are not…

This is one of the cool ideas not included in the 1800 human gene therapy trials because its still in animal models, not humans: Preclinical Therapy of Disseminated HER-2+ Ovarian and Breast Carcinomas with a HER-2-Retargeted Oncolytic Herpesvirus If Ive said it once, Ive said it 1000 times: ‘Cancer’ is not a monolithic entity. We…