Cancer

Tag archives for Cancer

Why havent we cured cancer yeeeeeet?

A neat paper was just published in Nature, where they did complete genome sequencing of the prostate cancer tumors from seven advanced/aggressive prostate cancer patients. The genomic complexity of primary human prostate cancer Why did they want to do this? They hoped to identify some new features of aggressive prostate cancer that could be exploited…

New cancer virus: Merkel Cell Polyomavirus

About this time last year, I wrote a post on a new cancer virus, XMRV. I had some reservations about that paper I reviewed. I have some reservations about XMRV–>prostate cancer as a whole (Im just not convinced yet. at all.). Its one thing to be skeptical about data, but its another to say ‘Hey,…

Oh no… Cedric died.

Oh no… Im genuinely crying over this. Cedric the Tasmanian Devil died. Here is the obvious reason for why I loved Cedric: But I loved Cedric for scientific reasons too. I thought he was going to help us save Tasmanian Devils from extinction. Dr. Alex Kreiss is the cute boy in that pic. Dr Kreiss…

As Carl Zimmer recently (and rightly) pointed out at the end of an article on epigenetics, while the concept of being able to alter our epigenetic profiles for therapeutic purposes is a really attractive concept, our current epigenetic therapy options are very, very messy. Like I said last week: Lemme give you an example. Lets…

HSV-1 and rhabdomyosarcoma update…

(previous post) Well shit. Shit. Goddammit.

WARNING: Get a box of Kleenex before you read this post! I am NOT joking. A few weeks ago I wrote a post on how scientists are using a genetically modified herpes simplex-1 virus to attack metastatic melanoma (an oncolytic, ie kills tumor cells, virus). The results of their clinical trials blew my mind. Today…

ERVs and Hodgkins lymphoma

Hey, you guys remember a while back, when Casey ‘Tits’ Luskin about peed his pants because ‘ERVS AR BE FUNKSHUNAL!!‘ Except, this is really another case of Creationists not knowing the difference between an ERV, solo LTRs, and random wayward ERV genes. And those solo LTRs that could theoretically still act as a promoter, really…

Using HSV-1 to cure metastatic melanoma

Metastatic melanoma is definately one of the Cancers That Suck. We basically have the same treatment options in 2010 as they had back in 1975… and not because we have chemotherapy/immunotherapy that works super great, no reason to change it. Our treatment options just suck, with horrible consequences– Say you have 100 friends that are…

ERVs, Epigenetics, and Testicular Cancer

Once again, ERVs, the best goddamn workhorse in the stable, have provided another great example for explaining How the World Works. This time? How a functional ERV protein interacts with normal cellular proteins to cause epigenetic changes that lead to cancer: Human Endogenous Retrovirus Protein Rec interacts with the Testicular Zinc Finger Protein and Androgen…