Cancer
Tag archives for Cancer
Epigenetics and Cancer: Making a messy mess messier.
Posted by ERV on June 29, 2010 As Carl Zimmer recently (and rightly) pointed out at the end of an article on epigenetics, while the concept of being able to alter our epigenetic profiles for therapeutic purposes is a really attractive concept, our current epigenetic therapy options are very, very messy. Like I said last week: Lemme give you an example. Lets…
HSV-1 and rhabdomyosarcoma update…
Posted by ERV on June 17, 2010 (previous post) Well shit. Shit. Goddammit.
Using HSV-1 to ‘cure’ rhabdomyosarcoma? *fingers crossed*
Posted by ERV on May 7, 2010 WARNING: Get a box of Kleenex before you read this post! I am NOT joking. A few weeks ago I wrote a post on how scientists are using a genetically modified herpes simplex-1 virus to attack metastatic melanoma (an oncolytic, ie kills tumor cells, virus). The results of their clinical trials blew my mind. Today…
ERVs and Hodgkins lymphoma
Posted by ERV on May 4, 2010 Hey, you guys remember a while back, when Casey ‘Tits’ Luskin about peed his pants because ‘ERVS AR BE FUNKSHUNAL!!‘ Except, this is really another case of Creationists not knowing the difference between an ERV, solo LTRs, and random wayward ERV genes. And those solo LTRs that could theoretically still act as a promoter, really…
Using HSV-1 to cure metastatic melanoma
Posted by ERV on April 7, 2010 Metastatic melanoma is definately one of the Cancers That Suck. We basically have the same treatment options in 2010 as they had back in 1975… and not because we have chemotherapy/immunotherapy that works super great, no reason to change it. Our treatment options just suck, with horrible consequences– Say you have 100 friends that are…
ERVs, Epigenetics, and Testicular Cancer
Posted by ERV on March 30, 2010 Once again, ERVs, the best goddamn workhorse in the stable, have provided another great example for explaining How the World Works. This time? How a functional ERV protein interacts with normal cellular proteins to cause epigenetic changes that lead to cancer: Human Endogenous Retrovirus Protein Rec interacts with the Testicular Zinc Finger Protein and Androgen…