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Janet D. Stemwedel (whose nom de blog is Dr. Free-Ride) is an associate professor of philosophy at San Jose State University. Before becoming a philosopher, she earned a Ph.D. in physical chemistry. Email her at dr.freeride@gmail.com.

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Research with human subjects:

Sex toys and human subjects at Duke University.

Category: Academia

At Terra Sigillata, Abel notes that the Director of Duke University's Catholic Center is butting in to researchers' attempts to recruit participants for their research. As it happens, that research involves human sexuality and attitudes toward sex toys. Here's how...

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Location, location, location: ethical considerations in where to run a clinical trial.

Category: Ethical research

A day later than promised, let's kick off our discussion of "Research Rashomon: Lessons from the Cameroon Pre-exposure Prophylaxis Trial Site" (PDF). The case study concerns a clinical trial of whether tenofovir, an antiretroviral drug, could prevent HIV infection. Before...

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Coming Monday: our discussion the case of a halted international clinical trial in Cameroon.

Category: Communication

Almost a month ago, I told you about a pair of new case studies released by The Global Campaign for Microbicides which examine why a pair of pre-exposure prophylaxis (PrEP) clinical trials looking at the effectiveness of antiretrovirals in preventing...

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Proposed guidelines for embryonic stem cells: applying new ethical rules to old research.

Category: Current events

You may have heard that the Obama administration has proposed new rules for federal funding of embryonic stem cell (ESC) research. (The proposed rules are available in draft form through the end of the public comment period; the NIH expects...

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Two new case studies on international clinical trials (and a plan to read them together).

Category: Communication

Earlier this week, I found out about a pair of new case studies being released by The Global Campaign for Microbicides. These cases examine why a pair of pre-exposure prophylaxis (PrEP) clinical trials looking at the effectiveness of microbicides antiretrovirals...

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A glimpse into how not to conduct an ethical drug trial.

Category: Current events

The Independent reports that drug giant Pfizer has agreed to pay a $75 million settlement nine years after Nigerian parents whose children died in a drug trial brought legal action against the company. It's the details of that drug trial...

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Is drug research on humans who are addicted to drugs ethical?

Category: Current events

DrugMonkey responds to the outgoing Drug Czar's deep concerns about research with illegal drugs conducted with subjects who are addicted to those drugs, those concerns reported in an article in the Washington Examiner. From that article: The federal government is...

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Your tax dollars at work: a look at clinical trials supported by NCCAM.

Category: Doing science for the government

In my last post, I started wading into the question of what kinds of ethical questions arise from clinical trials on "alternative" medical treatments, especially clinical trials supported by the National Center on Complementary and Alternative Medicine (NCCAM). The ethical...

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Conventional medicine, 'alternative' treatments, and the ethics of research with humans.

Category: Doing science for the government

A little while ago, PalMD put up a post at Whitecoat Underground about the current state of the National Center on Complementary and Alternative Medicine (NCCAM), especially at a moment in history when the federal government is spending loads of...

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A big pain for biomedicine: anesthesiologist commits massive research fraud.

Category: Academic integrity

The headlines bring news of another scientist (this time a physician-scientist) caught committing fraud, rather than science. This story is of interest in part because of the scale of the deception -- not a paper or two, but perhaps dozens...

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