As if we didn’t have enough “-omes” in biology, I have come across yet another one: the methylome. It’s beginning to sound like a Hindu temple up in here. My fascination with the -ome is well documented. I was made aware of the newest -ome in my collection by this preview of this article in Cell. The preview is entitled “The First High-Resolution DNA ‘Methylome’” and describes a paper announcing a high resolution map of DNA methylation in the Arabidopsis genome.
We can thank Andrew Feinberg for introducing the term methylome, which he defines as “a neologism that describes the complete set of DNA methylation modifications of a cell.” Check out this definition of neologism: “A meaningless word used by a psychotic.” Exactly. Enough with the -ome already.