evolgen

If you happen to be a yeast population geneticist, then you probably already know about the Saccharomyces Genome Resequencing Project. They have resequenced 32 strains of S. cerevisiae and 27 strains of S. paradoxus at between 1x and 3x coverage. The nice thing about resequencing is that SNP discovery and genotyping occur simultaneously. That’s in contrast to the human HapMap project which identified polymorphism in a few individuals, then searched for those polymorphisms in a larger panel. That means you can do some good population genetic analyses on the yeast data, which are not possible on the human data due to the ascertainment biases in the genotyping of HapMap individuals.

(Via Fungal Genomes and Comparative Genomics.)