Genomics:
I've told you before that I once dreamt of becoming a conservation geneticist. I major turning point for me occurred after I had completed rotations during my first year of grad school. I had to decide between two different labs:...
Posted on September 15, 2006 05:00 PM • 0 Comments
And they're doing it open access style. Jonathan Eisen and Michael Eisen have each published papers in the PLoS journals using newly available genome sequence data. Jonathan is lead on author on the paper describing the genome sequence of the...
Posted on September 8, 2006 08:00 AM • 1 Comments
Nobel Intent has an excellent summary of a paper in the PNAS pipeline on the origin of new exons in the human genome. The authors compared genes between humans and seven other vertebrates to identify newly arisen exons. They found...
Posted on September 7, 2006 05:30 PM • 2 Comments
David Haussler and colleagues have identified a 118 base pair sequence that has evolved really fast along the human lineage relative to the chimpanzee lineage (Carl Zimmer has a good review). In fact, this sequence differs by two base pairs...
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Posted on August 17, 2006 08:00 AM • 1 Comments
Here are three interesting items that I don't plan on blogging, but are worth linking to: Here is a news release on indel variation in humans. SNPs are so 20th century. Deletions, duplications, and insertions are the molecular polymorphisms of...
Posted on August 15, 2006 02:00 PM • 2 Comments
A few weeks ago I introduced y'all to Genoinformatics, the hot new abbreviation for Genome Informatics (some sort of derivative of Bioinformatics). I pointed out that I have quite a few international collaborators in this research area, including people in...
Posted on July 31, 2006 11:00 AM • 0 Comments
Or maybe his copy editor reads this blog. Either way, there are changes afoot at the NY Times. Three days ago I ragged on NY Times science reporter Nicholas Wade for using the word 'decode' when describing genome sequencing. In...
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Posted on July 21, 2006 09:00 AM • 1 Comments
If you could have practiced science in any time and any place throughout history, which would it be, and why? That's what they are asking us this week. And, once again, I'm going to skirt the question. You see, it...
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Posted on July 20, 2006 01:00 PM • 4 Comments
The National Human Genome Research Institute (NHGRI, sorry no clever acronym) has announced the next primate genome to be sequenced: the white cheeked gibbon (pictured right). This genome is of particular interest due to the large amount of segmental...
Posted on July 20, 2006 11:00 AM • 0 Comments
The NY Times has chimed in on cheap DNA sequencing with this article from Nicholas Wade. Wade's article deals with medical applications of affordable whole genome sequencing technologies (with the goal being the $1000 genome). The article, however, is cringe-inducing...
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Posted on July 18, 2006 12:00 PM • 1 Comments
Here is some light reading for your Sunday: Mosquitoes sing to each other by flapping their wings. This paper reports sexually dimorphic responses to wing beat patterns in mosquitoes (PZ Myers has a good review). This leads me to wonder...
Posted on July 16, 2006 09:00 AM • 0 Comments
The Scientist is linking to an imaginary1 article from PNAS in which researchers compare the cost of sequencing microbial (I'm guessing they mean bacteria) genomes using the traditional Sanger method and the hot new technology developed by 454. Not so...
Posted on July 13, 2006 09:00 AM • 3 Comments
The genome encodes all of the RNAs and contains sequences responsible for the transcription of those RNAs and the proper folding and wrapping of the cromosomes. The RNAs encoded by the genome are collectively known as the transcriptome. The transcripts...
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Posted on July 12, 2006 09:00 AM • 6 Comments
Andy Clark has written a review of comparative evolutionary genomics for Trends in Ecology and Evolution. His review deals with identifying functional regions of the genome and inference of both positively and negatively selected sequences. Clark is one of the...
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Posted on June 15, 2006 09:00 AM • 0 Comments
Another review of Michael Ashburner's book Won for All is available on PLoS Biology. PZ Myers also wrote a review of the book, and the two pieces complement each other nicely....
Posted on June 14, 2006 03:30 PM • 0 Comments
John Hawks' really needs to permit comments on his blog. I mean, without comments, is it really a blog? I bring this up because this post really belongs in the (non-existent) comments of this post from Hawks. Hawks discusses this...
Posted on June 3, 2006 10:00 AM • 2 Comments
We talk about molecular population and evolutionary GENETICS and GENOMICS. You know, the caliper measurement of a gene's evolvability in moles.
