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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

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November 30, 2008

The ACTN3 sports gene test: what can it really tell you?

Category: genetics of normal variation

The NY Times reports on the launch of a genetic test for athletic performance, aimed at the parents of young children. How useful is this test likely to be to its customers?

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November 20, 2008

Genes don't add much value for predictions of type 2 diabetes risk

Category: disease genetics

At Gene Expression, p-ter points to two studies in this week's New England Journal of Medicine examining the predictive value of known genetic markers for type 2 diabetes. Both studies find the additional predictive power of the genetic markers beyond...

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FDA interested in collaborating with personal genomics companies

Category: personal genomics

The US Food and Drug Administration is currently looking into collaborating with personal genomics companies to track adverse drug reactions.

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November 19, 2008

Embryo screening for common diseases: coming soon?

Pre-natal genetic screening for common diseases like type 2 diabetes is becoming technically feasible - but it's unlikely to be widely adopted in the near future, for several important reasons.

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November 18, 2008

Limitations of 1000 Genomes Project

A Nature News article discusses the ongoing 1000 Genomes Project, an international effort planning to sequence 1,200-1,500 human genomes. The discussion springs from project co-chair David Altshuler's update at last week's American Society of Human Genetics meeting on the progress...

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November 15, 2008

Genetic Genealogist deconstructs ASHG criticisms of ancestry testing

Category: genetic ancestry testing

Blaine Bettinger at the Genetic Genealogist has an extensive and thoughtful critique of the American Society of Human Genetics' recently released statement on genetic ancestry testing (pdf). (You can read about the Society's statement at GenomeWeb News and Science Now;...

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November 14, 2008

Sequencing one genome at a time is so last week

Category: 1000 genomes project

Last week I posted on the publication of three papers in Nature describing whole-genome sequencing using next-generation technology: one African genome, one Asian genome, and two genomes from a female cancer patient (one from her cancer cells and one from...

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November 11, 2008

Australia to get its own personal genomics company?

Category: personal genomics

A new personal genomics company, Lumigenix, is poised to launch its service in Australia - but the newcomer will face both stiff competition and a hostile regulatory environment.

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November 10, 2008

Do It Yourself: searching for evolution's signature in 53 human populations

Category: genome-wide scans for selection

A new online browser offers insight into natural selection in humans using genome-wide genetic variation data from 53 populations.

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November 7, 2008

Not that I'm bitter or anything...

Category: personal genomics

deCODE CEO Kari Stefansson on the recent award of Time magazine's "Invention of the Year" to personal genomics competitor 23andMe: Despite the fact that we launched our test first - so we basically invented this, and also 23andMe is using...

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