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Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.
Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.
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December 22, 2008
Category: personal genome project
Emily Singer has a fantastic article in MIT's Technology Review reviewing the current state of play in human genomics. A curious highlight for me was this panel of mug-shots from the PGP-10, the 10 high-profile volunteers currently having their genomes...
Posted by Daniel MacArthur at 6:38 AM • 6 Comments •
December 19, 2008
Category: bioinformatics
Web-comic xkcd has some on-target advice for high-schoolers, particularly those interested in a career in genetics...
Posted by Daniel MacArthur at 1:30 PM • 8 Comments •
Category: zs genetics
Sure is news to me - from popsci.com: Archon X Prize for Genomics Purse: $10 million Goal: Sequence 100 human genomes in 10 days for $10,000 per genome or less Status: ZS Genetics, which is developing an approach that replaces...
Posted by Daniel MacArthur at 10:15 AM • 2 Comments •
December 18, 2008
Category: personal genomics
2008 was an exciting year for the embryonic industry of personal genomics - here are some of the highlights.
Posted by Daniel MacArthur at 12:00 PM • 1 Comments •
December 17, 2008
Category: whole-genome sequencing
David Ewing Duncan has a piece in Portfolio.com about Complete Genomics, a DNA sequencing company that launched back in October promising to offer whole-genome sequencing for $5000 by mid-2009. Complete Genomics is based on some allegedly powerful new technology (here's...
Posted by Daniel MacArthur at 5:00 PM • 0 Comments •
December 16, 2008
Category: omics
From a recent paper in Nature Reviews Microbiology, it's probiogenomics! The human body is colonized by an enormous population of bacteria (microbiota) that provides the host with coding capacity and metabolic activities. Among the human gut microbiota are health-promoting indigenous...
Posted by Daniel MacArthur at 9:20 AM • 3 Comments •
December 15, 2008
Category: genetics of normal variation
Two massive genome-wide association studies of human body mass index provide a harvest of new genes, but little in the way of increased power to predict obesity risk.
Posted by Daniel MacArthur at 7:05 PM • 3 Comments •
December 12, 2008
Category: genetic ancestry testing
A new paper provides even more detail on fine-scale population structure within Finland.
Posted by Daniel MacArthur at 6:22 AM • 3 Comments •
December 11, 2008
Category: hiv susceptibility
A new study finds a striking overlap between risk genes for type 1 diabetes and celiac disease - and a novel genetic link between these two diseases and HIV susceptibility.
Posted by Daniel MacArthur at 10:35 AM • 0 Comments •
December 10, 2008
Category: whole-genome sequencing
Patents on individual genes are complicating the emergence of whole-genome analysis services - but change may be on the way.
Posted by Daniel MacArthur at 8:13 PM • 11 Comments •
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