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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

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April 30, 2009

Massive study of African genetic diversity

Category: evolutionary genetics

The most comprehensive analysis to date of the genetic diversity within Africa has been published in the journal Science - and it is a breathtaking piece of work.

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Sequenom reveals prenatal Down syndrome test data are "questionable"

Category: pre-natal genetic diagnosis

For those who have been too distracted by swine flu to notice: shares of the biotech company Sequenom have plummeted by 77% after the company announced that the extremely promising initial results for its SEQureDx Down syndrome test - which...

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April 28, 2009

Common genetic variant linked with autism - but with modest effects

Category: genome-wide association studies

A common genetic variant is reported in Nature as being associated with an increased risk of autism - but the effects on disease risk are modest, consistent with a generally disappointing yield for studies of common variants in psychiatric diseases.

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Genetics of complex traits in Europeans and East Asians: similarities and differences

Category: genome-wide association studies

A large Korean study takes a detailed look at the genetic variants associated with 8 different complex traits - and provides an intriguing insight into the differences in the genetic architecture of variable traits between human populations.

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April 27, 2009

23andMe to offer genetic testing through San Diego healthcare organisation

Category: personal genomics

Personal genomics company 23andMe has teamed up with a San Diego health service provider to provide its genome scans to patients. But will the genetic risk information provided by 23andMe actually have a positive impact on patient health?

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Photo Synthesis

I usually try to maintain a fairly single-minded focus on genomics on this blog, but Alex Wild's current series of post on insect photography over at Photo Synthesis is simply stunning. Anyone interested in either photography or entomology - or...

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April 26, 2009

Personal Genome Project looking for next wave of volunteers

Category: personal genome project

The Personal Genome Project is looking for 100 more volunteers to have their complete genome sequenced. The catch: participants will be encouraged to deposit their genetic and health data online for public viewing.

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April 25, 2009

Knome's whole genome sequencing auction goes live on eBay

Category: whole-genome sequencing

The auction of a whole-genome sequencing service that I scoffed at a few days ago is now live on eBay - serious bidders only, please, and bids start at $68,000.Here's what you get for your suitcase of cash:Personal whole genome...

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April 24, 2009

Germany to ban DTC genetic testing, non-medical embryo screening

Category: direct-to-consumer genetic testing

Associated Press reports that Germany will likely soon pass regressive laws limiting the use of genetic testing: The German parliament approved legislation Friday limiting the use of genetic testing in an effort to prevent the technology's abuse. The law, which...

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April 22, 2009

Knome to auction whole genome sequencing on eBay: how much is yours worth?

Category: personal genomics

Personal genome sequencing company Knome plans to offer a complete genome sequence to the highest bidder on eBay - with a starting bid of $68,000. But how much is a complete genome sequence actually worth?

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