European Genetics and Anthropology has a neat little tutorial
that may be of interest for genetic hobbyists: it provides instructions on how to run the program STRUCTURE
on your own genetic data generated by a personal genomics company such as 23andMe
STRUCTURE is an extremely popular tool among researchers working in population genetics, which allows you to generate plots showing estimates of the proportion of an individual’s genome belonging to different population clusters.
The tutorial on the blog shows you how to run your analysis using a subset of just 125 markers selected from your genetic data. That’s enough to get a sense of what’s going on, but of course having access to more than 500,000 markers from a genome scan theoretically allows you to perform a more powerful analysis using a much larger set of markers (and comparing to, say, the freely available SNP data from the Human Genome Diversity Panel
It’s great to see tools developed by academia being democratised by personal genomics hobbyists. One major benefit: if your personal genomics company does go bankrupt
, so long as you’ve downloaded your data you can still analyse your genetic ancestry…
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