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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

Daniel also blogs about personal genomics at Genomes Unzipped.

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July 30, 2010

Personal genomics links

Category: personal genomics

A recap of useful and interesting links from the increasingly chaotic world of personal genomics, with an emphasis on the current regulatory turmoil in the US.

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July 29, 2010

Protecting consumers from their own genetic data will come at a cost

Category: commercial genetic testing

Investigations launched by the FDA and US Congress have potentially set the stage for a large-scale regulatory crackdown on the embryonic direct-to-consumer genetic testing industry. Such a move would be premature, and would do more harm than good to consumers. The industry needs to change, but a more careful, measured approach based on increasing the transparency of genetic tests is the best way forward.

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July 22, 2010

A sad day for personal genomics

Category: FDA

The news for the embryonic personal genomics industry keeps getting worse: today's Congress hearing was a brutal evisceration, aided by a new report on a sting operation aimed at genetic testing companies. As the regulators close in, what does the future hold for those of us seeking to explore our own genetic information?

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July 21, 2010

Did Washington Post's Rob Stein exaggerate negative stories about personal genomics?

Category: FDA

An article in the Washington Post by reporter Rob Stein includes several "negative experiences" from personal genomics customers. The fact that so few such experiences could be found tells us something about the general satisfaction of customers with their personal genomic data - and a blogger claims that even these anecdotes have been exaggerated in the article for dramatic effect.

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July 19, 2010

How to interpret a genome-wide association study

Category: genome-wide association studies

Every issue of Nature Genetics is packed full of them, and they're the basis for the risk predictions offered by every personal genomics company - but how do you make sense of a genome-wide association study? How can you tell...

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July 13, 2010

Why sequencing matters for personal genomics

Category: genomes unzipped

The first ever post on the new group blog I announced yesterday, Genomes Unzipped, is now live: it's Luke Jostins of Genetic Inference talking about the importance of sequencing for the future of personal genomics. Here's a taste:There is a...

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July 12, 2010

Announcing Genomes Unzipped, a new group blog on personal genomics

Category: genomes unzipped

I've started a new group blog about personal genomics, Genomes Unzipped, with a group of fellow scientists and like-minded bloggers.

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Rob Stein needs your positive experiences of personal genomics

I've just been forwarded an email that was originally sent to the National Society of Genetic Counsellors email list on behalf of a reporter with the Washington Post:Dear NSGC Members, Washington Post reporter Rob Stein has interviewed NSGC President Liz...

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July 7, 2010

23andMe contributes to longevity GWAS controversy

Category: genome-wide association studies

As an addendum to my previous post on the controversial "longevity genes" study, you should go and check this out. It's a post on the blog of personal genomics company 23andMe, and it's a pretty impressive piece of scientific dissection of...

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Serious flaws revealed in longevity genes study

Category: genome-wide association studies

A recent paper in Science reported finding a strong genetic signature associated with exceptional longevity. However, the key findings of the paper already seem to be unravelling, with a series of prominent geneticists publicly criticising the study for major methodological flaws.

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