transcriptome sequencing
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Category archives for transcriptome sequencing
Using new sequencing technology to look at gene expression in a single cell
Posted by Daniel MacArthur on April 7, 2009
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Jeffrey Perkel at Biotechnically Speaking has a great overview of a recent paper in Nature Methods (see also coverage at GenomeWeb). The study in question used second-generation sequencing (with the ABI SOLiD system) to peer inside a single cell isolated from a mouse embryo. By sequencing the messenger RNA (mRNA) produced by the cell’s genome…