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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

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Skeptics:

genetic ancestry testing:

UK backing away from controversial refugee tests?

Category: genetic ancestry testing

Last week I noted a highly controversial plan by the UK Border Agency to begin using DNA and isotope testing to help determine the geographical origins of refugees, for use in making decisions about whether or not to grant...

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Outrage over DNA testing for UK asylum seekers

Category: genetic ancestry testing

The UK Border Agency has sparked outrage from scientists and refugee advocates by proposing the use of genetic and isotope tests for the determination of geographical ancestry in making decisions on refugee status.

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Genetic Genealogist on 23andMe's ancestry testing

Category: direct-to-consumer genetic testing

Genetic genealogist Blaine Bettinger discusses the results of his genetic ancestry analysis by personal genomics company 23andMe.

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Gene Genie #42 - focus on personalised genetics

Category: direct-to-consumer genetic testing

Welcome to the 42nd edition of Gene Genie, the blog carnival of clinical genetics and personalised medicine - this time with a special focus on personalised genetics.

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The diversification of consumer genomics

Category: personal genomics

The major players in the consumer genomics field have worked hard to distinguish themselves from their competitors, and steer clear of the "clinical diagnostics" label. A newcomer to the field, Counsyl, suggests the field will soon become even more diverse.

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More on Finnish population substructure

Category: genetic ancestry testing

A new paper provides even more detail on fine-scale population structure within Finland.

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Genes and the social flexibility of race

Category: genetic ancestry testing

A few days ago I posted a picture depicting the genetic ancestry of African-Americans modelled as a linear combination of European and Nigerian genetic clusters (reproduced below). Dienekes has some thoughtful comments on the same picture. Meanwhile, Razib comments on...

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Finnish population structure won't persist much longer

Category: genetic ancestry testing

In my previous post on Finnish population clustering I should have emphasised that the map was constructed only from individuals who had both parents from the same geographic/linguistic region; this obviously provides a lot more power to detect a correlation....

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Genetics and geography in Finland

Category: genetic ancestry testing

Here's a figure from a brand new paper on the genetics of metabolic traits in a large Finnish cohort (which I'll be posting about in more detail shortly): On the left is a map of the counties the samples were...

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Genetics of gene expression in African-Americans: ominous news for personal genomics?

I was planning to write a long article on this recent paper in PLoS Genetics, but p-ter at Gene Expression and G at Popgen ramblings have both covered the central message very well. So if you haven't read those articles,...

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