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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

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genetics of normal variation:

23andMe gets scooped on hair curl genes

Category: genome-wide association studies

Personal genomics company 23andMe announced novel genetic associations with hair curl at the recent ASHG meeting - but these findings have now been scooped by a publication from an academic consortium.

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23andMe presents novel genetic associations at American Society of Human Genetics meeting

Category: ashg2009

Personal genomics company 23andMe presented today at the American Society of Human Genetics meeting on novel genetic associations generated by the company using data from their customer base. The presentation showed that the company is capable of doing solid science, although it also raised worrying questions about the validity of survey results from customers who've already seen their genetic data.

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Chinese summer camp to offer genetic tests for IQ, athletic performance, emotional control

Category: genetics of intelligence

A Chinese summer camp is offering parents the opportunity to spend $880 on genetic tests purporting to predict their child's athleticism, intelligence and personality.

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Genetics of complex traits in Europeans and East Asians: similarities and differences

Category: genome-wide association studies

A large Korean study takes a detailed look at the genetic variants associated with 8 different complex traits - and provides an intriguing insight into the differences in the genetic architecture of variable traits between human populations.

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NIH offers $2 million to fund mapping of genetic variation to gene expression

Category: genetics of gene expression

GenomeWeb Daily News points to a new funding opportunity from the US National Institutes of Health (NIH) for researchers interested in studying the link between genetic variants and variation in the expression levels of genes.This is an incredibly important area...

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Genes vs environment: a false dichotomy

Category: gene-environment interactions

Neuroscientists Sam Wang and Sandra Aamodt have a guest post on Olivia Judson's NY Times blog discussing the complex interplay between genes and environment in the determination of personality traits. A taste:So some of the effects that we call "genetic"...

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Race and intelligence: the debate continues

Category: race

The debate over the validity of research into racial differences in intelligence continues in the Correspondence section of the latest issue of Nature.

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Predicting eye colour from genes

Category: genetics of normal variation

A recent study shows that genetic information is sufficient to generate extremely accurate predictions of eye colour - predictions that will prove useful in forensic applications, and potentially may be used by parents for "cosmetic" screening of IVF embryos.

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Predicting height: the Victorian approach beats modern genomics

Category: genetics of normal variation

A recent paper shows that, despite massive genome-wide association studies, height predictions using known genetic markers are still far less accurate than those using parental height alone.

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Predicting faces from genes

Category: genetics of normal variation

Researchers are studying the genetic basis of variation in face shape - raising the possibility of predicting faces from DNA, either for forensic work or (more controversially) for IVF embryos via pre-implantation genetic testing.

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