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Genetic Future

Commentary on human genetics and evolution, direct-to-consumer genetic testing, and the personal genomics industry.

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Daniel MacArthur
I write about the genetic and evolutionary basis of human variation, and the companies trying to sell you information about your genome.

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Blogs I read:

Consumer Genomics:

Genomic Science:

Genetics/Evolution Blogs:

General Science:

Corporate Blogs:

Skeptics:

next-generation sequencing:

IBM's foray into nanopore sequencing: are they serious contenders?

Category: next-generation sequencing

The announcement that IBM is entering the DNA sequencing race has created media excitement, but as yet there's nothing to suggest that IBM is a serious competitor to better-established platforms such as Oxford Nanopore.

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News in genomics

Category: next-generation sequencing

IBM is moving into the DNA sequencing market, the Genomics Law Report has launched a great new series on ethical, legal and social issues in genomics, and a new program has been launched to teach medical students about recent developments in genomics - including an opportunity to get themselves tested.

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The informatics of new sequencing technologies

Category: next-generation sequencing

Two interviews in Bio-IT World shed light on the rapidly evolving world of new sequencing technology, and the informatic challenges created by that evolution.

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Illumina delivers its first commercial personal genome sequence

Category: next-generation sequencing

Sequencing company Illumina has delivered its first commercial personal whole genome sequence to entrepreneur Hermann Hauser.

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Complete Genomics back in action after 6 month funding delay

Category: next-generation sequencing

Complete Genomics, the company that promises complete human genome sequences for $5,000, has finally received the funding it needed to construct its first commercial facility in Silicon Valley. I talked to the company's CEO and one of its directors about the company's goals over the next 18 months.

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Another genomics blog to follow: Pathogenomics

Category: next-generation sequencing

I've just discovered a very promising new blog in the genomics sphere (well, technically it's a newly relaunched blog) run by a group at the University of Birmingham.Two posts by Nick Loman are of immediate interest to readers here. Firstly, I...

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Pacific Biosciences raises $68M for third-gen sequencing development

Category: next-generation sequencing

The announcement of the Helicos genome sequence (which I've already discussed in detail) engendered a huge amount of media interest, sometimes for the wrong reasons. Having the media attention directed elsewhere in the third-generation sequencing space was clearly an unwelcome experience...

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What is it with rich white guys and genome sequences?

Category: next-generation sequencing

The widely-reported "price drop for genome sequencing" due to third-generation sequencer Helicos is an illusion.

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Helicos co-founder sequences own genome using single-molecule technology

Category: next-generation sequencing

Stephen Quake, co-founder of DNA sequencing start-up Helicos, has sequenced his own genome using the company's single-molecule sequencing technology - but we still haven't reached the cost and accuracy points required to trigger a revolution in human genome sequencing.

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Guest post: Luke Jostins on the twice-sequenced genome

Category: guest post

Luke Jostins of Genetic Inference critiques a recent paper in Genome Research showcasing the first published human genome sequence generated using SOLiD technology.

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