Gene Expression

New PLOS paper, Geographic Patterns of Genome Admixture in Latin American Mestizos. Nothing new, but pushing the ball forward….


A = autosomal
X = X chromosomal

Related: Genetics, the myth-buster? The case of Argentina.


  1. #1 Luis
    March 21, 2008

    “Nothing new”, as you say but still interesting. Anyhow there are a couple of things that drew my attention:

    1. The graph showing the apportion of native blood by linguistic/geographical groups (figure 5) shows that many mestizos have not just native blood from the local area but from all the continent without much distinction (for instance, Mexico City mestizos have as much meso/north American native blood as South American). This probably implies that mestizo people moved around the Spanish colonial empire pretty much (at least that’s my first thought).

    2. A couple of samples (Oriente-Guatemala and Salta-Argentine) show equal apportion of European autosomal and X-chr genetics. If I don’t understand wrongly, that means that admixture in those populations was balanced with similar male and female European input, right? I find this somewhat strange. This is a contrast to the general trend that is of significatively more autosomal than X-chr European apportion (mainly male input) and to the systematically much more X-chr (mainly female) than autosomal African input (that is about the same in all samples).

    I hope I’m not reading that wrong but, as I see it, basically 67% of the X-chr is statistically female in origin in contrast with 50% of the autosomal pool, right?

  2. #2 razib
    March 21, 2008

    re: #1, the paper somewhat argues the opposite based on their data.

    re: #2, about right.

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