Gene Expression

Notes on Sewall Wright: Wright’s F-statistics:

A preliminary question is one of terminology. What, if anything, does the letter ‘F’ stand for? One plausible answer is that it stands for ‘fixation’, since among other things the F-statistics can be used to measure the rate at which alleles tend to be ‘fixed’. Wright himself in his later writings sometimes refers to F as an ‘index of fixation’.

Believe it or not, Fst is one of thos population genetic concepts you’ve almost certainly encountered no matter your background.

Related: On Reading Wright, Notes on Sewall Wright: Path Analysis and Notes on Sewall Wright: the Measurement of Kinship.


  1. #1 IanR
    May 20, 2008

    Wow. I had never hovered over those links you always have above those short quotes. I never knew GNXP Classic existed. I just poked around a bit there. I had no idea what I’d been missing out on.

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