Gene Expression

R. A. Fisher and Epistasis

David takes a slight detour in this Sewall Wright, series, R. A. Fisher and Epistasis:

My next note on Sewall Wright will cover the exciting subject of the adaptive landscape. As every schoolboy knows, Wright considered epistatic gene interactions very important in determining the ‘peaks’ of the landscape. A sharp contrast is sometimes drawn between Wright and R. A. Fisher in this respect….

This is a preamble to a very long and dense post. If it interests you in the subject, I’d also recommend Epistasis and the Evolutionary Process. You might also check out this older post of mine on evolutionary epistasis.

Related: Notes on Sewall Wright: Population Size, Notes on Sewall Wright: the Measurement of Kinship, Notes on Sewall Wright: Path Analysis, On Reading Wright and Notes on Sewall Wright: Migration.