Gene Expression

Archives for March, 2009

John Hawks & Daniel MacArthur have already pointed to a new paper in Genome Research, Signals of recent positive selection in a worldwide sample of human populations. As Dan notes, it’s Open Access, so you can read the PDF yourself. That being said, “Just read it!” might be somewhat a tall order if you don’t…

23andMe = Terrorists?

I thought this Genetic Future post was an exaggeration, as it seemed to indicate that the Gene Sherpa was accusing 23andMe of terrorism. I thought there has to be context, right? Uh, not really: In healthcare, imagine if your doctor was found to be breaking the law. Stole from Medicare? Non-Compliance with State regulations? Spousal…

Swedish stereotypes, true & false

Sweden Says No to Saving Saab: Which makes it all the more wrenching that the Swedish government has responded to Saab’s desperate financial situation by saying, essentially, tough luck. Or, as the enterprise minister, Maud Olofsson, put it recently, “The Swedish state is not prepared to own car factories.” Such a view might seem jarring,…

Twists in Out-of-Africa

Early modern human diversity suggests subdivided population structure and a complex out-of-Africa scenario: The interpretation of genetic evidence regarding modern human origins depends, among other things, on assessments of the structure and the variation of ancient populations. Because we lack genetic data from the time when the first anatomically modern humans appeared, between 200,000 and…

Genetics of human pigmentation

Richard Sturm in Human Molecular Genetics has a really good review of the current state of pigmentation genetics, with a human centric focus: The genetic basis underlying normal variation in the pigmentary traits of skin, hair and eye colour has been the subject of intense research directed at understanding the diversity seen both between and…

The Intersection has moved

Just a heads up, they’re had Discover Blogs now. Just want to note, I welcomed Tapped (which Chris Mooney was instrumental in setting up) to the blogosphere in April of 2002. Chris’ acknowledgment of welcome, and my own pre-blogspot weblog, have been vaporized by the digital dustbin, but I wanted to put it into the…

The great Malthusian race

The rise in eczema, or asthma, or the general return of infectious disease, reminds one that though we live in a post-Malthusian Age generally, many of the truths of earlier times hold. While with physical technology we can rest assured that the feature-set and power will increase monotonically over time as if it is a…

The GSS has a variable, ODDS1, which represents the question: Now, think about this situation. A doctor tells a couple that their genetic makeup means that they’ve got one in four chances of having a child with an inherited illness. Does this mean that if their first child has the illness, the next three will…

A few years ago a brown friend of mine complained that there were all these diseases which non-white people were susceptible to at a higher rate (e.g., Type II Diabetes, hypertension, ateriosclerosis, etc.), perhaps the white race was really superior (or medical geneticists were entering into a conspiracy to prove that this was so). So…

Needed for AIG and the TARP: Silicon Valley Compensation Schemes: The engineers of Silicon Valley startups are significantly smarter and work a lot harder than do the traders of Wall Street. Some of the engineers of Silicon Valley make fortunes: they are compensated with relatively low salaries and large restricted equity stakes in the startup…