As you can see by looking to the left (right below the cutest kid that ever was) I'm participating in DonorsChoose this year. You can of course donate to any project you think is worthy, but my current list is biased in two directions:
1) Need
2) Biology
Since last fall a lot as changed economically and socially, and of course people on the margins are squeezed the most. Those of us not on the margins have seen hardship, or seen those around us subject to hardship, but really this sort of thing is normalized to our relative context. Many of the projects require small amounts of money; this is leverage in a good way. For those readers who are skeptical of the efficacy of more capital inputs into education, I think on the primary & secondary level there are certainly some returns on investment to be had.