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Human evolution, genetics, genomics and their interstices
Category: Anthroplogy
In my discussion with Eliezer I referred to "recreational genetics." Basically, "for entertainment purposes only" genetics. For example, someone with blue eyes confirming that they have the alleles on OCA2 & HERC2 associated with blue eyes. Or a man with...
Posted by Razib Khan at 6:35 AM • 5 Comments •
Category: Evolution
After watching Creation last week I decided to take the plunge and read Origin of Species. As I've mentioned before I did read Origin early in my teen years, but in hindsight with minimal comprehension. Since then I've occasionally started...
Posted by Razib Khan at 5:15 AM • 10 Comments •
Category: Genetics
A few days ago I discussed a new paper which explores the patterns of natural selection in the genome of the X chromosome. As you know the X is "carried" disproportionately by females, as males have only one copy, so...
Posted by Razib Khan at 5:00 AM • 3 Comments •
Category: Genetics
Could be the title of the paper. Anyway, Genome-wide association mapping identifies multiple loci for a canine SLE-related disease complex:...Incidences of specific diseases are elevated in different breeds, indicating that a few genetic risk factors might have accumulated through drift...
Posted by Razib Khan at 3:27 AM • 1 Comments •
Category: Genetics
Update: Also see p-ter at Gene Expression Classic. Follow up on yesterday's post on the new Dickson et al. paper from David Goldstein's lab, A New Way to Look for Diseases' Genetic Roots: The Icelandic gene-hunting firm deCODE genetics, which...
Posted by Razib Khan at 4:16 PM • 0 Comments •
Category: Genetics
One of the more substantive consequences of the powerful new genomic techniques has been in the area of ancient DNA extraction and analysis. The Neandertal genome story is arguably the sexiest, but closer to the present day there've been plenty...
Posted by Razib Khan at 9:48 AM • 1 Comments •
Category: Genetics
David Goldstein, a geneticist at Duke, has critiqued the current focus on large-scale genomwide associations before. Now he is taking to the next step, as his group has a paper out which suggests that the reason that association studies have...
Posted by Razib Khan at 10:03 PM • 5 Comments •
Category: Genetics
In Bats and Whales, Convergence in Echolocation Ability Runs Deep: ..."However, it is generally assumed that most of these so-called convergent traits have arisen by different genes or different mutations. Our study shows that a complex trait -- echolocation --...
Posted by Razib Khan at 5:48 PM • 1 Comments •
Category: Anthroplogy
Changes in human diet driven by cultural evolution seem to be at the root of many relatively recently emerged patterns of genetic variation. In particular, lactase persistence and varied production of amylase are two well known cases. Both of these...
Posted by Razib Khan at 5:59 AM • 38 Comments •
Category: Genetics
In the wake of my post on selection and variation in dog skull shape, I thought it would be useful to point to this short paper, A canine chromosome 7 locus confers compulsive disorder susceptibility. Here's the conclusion: The highly...
Posted by Razib Khan at 7:45 PM • 4 Comments •
