Genetics

Gene Expression

Category archives for Genetics

The language families of Europe fall into a few broad categories. There are the Indo-European languages, which include the Romance, Germanic, Slavic and Celtic subgroups, along with Greek and Albanian. The Iranian languages and most of the languages of India are also Indo-European. Then there are the languages of Finland and Hungary, which are hypothesized…

To the left I’ve juxtaposed the images of the four Bushmen males whose genomes were analyzed in the recent Nature paper and compared to Desmond Tutu. I’ve added to the montage a photo of a Swedish and Chinese man. The Nature paper looked at the HapMap data sets which had within them whites from Utah,…

The Bushmen & the Bantu

There’s a new paper out in Nature which details the genomes of several Bushmen, and how they relate to other humans, and one particular Bantu speaking individual, archbishop Desmond Tutu. It’s open access, Complete Khoisan and Bantu genomes from southern Africa. I haven’t read the whole thing, but it is probably best to check out…

Lactase persistence results in the ability to break down the lactose sugar in milk as an adult, lactase being the enzyme which breaks down lactose. If one can not digest that sugar, and still consumes milk, then one exhibits the symptoms of lactose intolerance. Originally diagnosed as a disease it has come to light that…

Congratulations to Dr. Daniel MacArthur & the Mrs.

Dr. Daniel MacArthur reports on shenanigans in his homeland, Australian insurance company offers discounted genome scans to customers; read the fine print!: A reader pointed me to this article in the Australian news: it appears that a major Australian insurance company, NIB, is planning to offer half-price genome scans from personal genomics company Navigenics to…

Dr. Daniel MacArthur returns from hiatus, and observes that deCODE is now in the advanced stages of corporate death. Pointers to a Newsweek article and other bloggers at Dr. MacArthur’s post. Over at Gene Expression Classic p-ter points out that Small genetic effects do not preclude drug development (one of the rationales given for why…

One of the interesting aspects ensuing from the rise of molecular phylogenetics is that the trees are generally concordant in broad strokes with older research which was based on morphology. This is not too surprising, as nature does tend to show some intelligible patterns which can be cross-checked with different methods (e.g., the fact of…

Genome-Wide Associations in Asians

Genome-Wide Association Study in Asian Populations Identifies Variants in ETS1 and WDFY4 Associated with Systemic Lupus Erythematosus: In this study, we first conducted a genome-wide association study in a Hong Kong Chinese population, followed by replication in three other cohorts from Mainland China and a cohort from Thailand, which totaled 3,300 Asian patients and 4,200…

Aurochs resurrection project

Breeding Ancient Cattle Back from Extinction: The only place to see an aurochs in nature these days? A cave painting. The enormous wild cattle that once roamed the European plains have been extinct since 1627, when the last survivor died in a Polish nature reserve. But this could soon change thanks to the work of…