Africa

Gene Expression

Tag archives for Africa

To the left I’ve juxtaposed the images of the four Bushmen males whose genomes were analyzed in the recent Nature paper and compared to Desmond Tutu. I’ve added to the montage a photo of a Swedish and Chinese man. The Nature paper looked at the HapMap data sets which had within them whites from Utah,…

The tales that the X chromosome tells

Highly Punctuated Patterns of Population Structure on the X Chromosome and Implications for African Evolutionary History: It is well known that average levels of population structure are higher on the X chromosome compared to autosomes in humans. However, there have been surprisingly few analyses on the spatial distribution of population structure along the X chromosome.…

I was doing some exploring of the effect of a transition to agriculture on human height. Until the past few centuries humans were much shorter than they had been during the Ice Age. In the process I came upon some interesting data. Height, health, and development: Adult height is determined by genetic potential and by…

Africa’s urban poor becoming obese

Yeah, you read that right. Overweight and obesity in urban Africa: A problem of the rich or the poor?: Descriptive results showed that the prevalence of urban overweight/obesity increased by nearly 35% during the period covered. The increase was higher among the poorest (+50%) than among the richest (+7%). Importantly, there was an increase of…

Africans, disease, history and ecology

Interesting review paper on disease and Sub-Saharan African, Neglected Tropical Diseases in Sub-Saharan Africa: Review of Their Prevalence, Distribution, and Disease Burden: The neglected tropical diseases (NTDs) are the most common conditions affecting the poorest 500 million people living in sub-Saharan Africa (SSA), and together produce a burden of disease that may be equivalent to…

African genetic structure

I’ve been fine tuning Ubuntu all day with goodies and getting drivers to work right, so I missed this paper on African genetics: Africa is the source of all modern humans, but characterization of genetic variation and of relationships among populations across the continent has been enigmatic. We studied 121 African populations, 4 African American…

The secret history of Africa

In light of the relatively recent interaction of Bantu farmers and Pygmies in Central Africa, this paper is of note, Genetic and demographic implications of the Bantu expansion: insights from human paternal lineages: The expansion of Bantu languages, which started around 5,000 years before present (YBP) in west/central Africa and spread all throughout sub-Saharan Africa,…

Another response by Etienne Patin, lead author of Inferring the Demographic History of African Farmers and Pygmy Hunter-Gatherers Using a Multilocus Resequencing Data Set, to a follow up post:

The leader author of the PLoS Genetics paper Inferring the Demographic History of African Farmers and Pygmy Hunter-Gatherers Using a Multilocus Resequencing Data Set, which I blogged a few days ago left a clarifying comment: