genetic relatedness
Gene Expression
Tag archives for genetic relatedness
93 ancestrally informative markers to categorize them all
Posted by Razib Khan on July 30, 2009 An ancestry informative marker set for determining continental origin: validation and extension using human genome diversity panels: Results In this study, genotypes from Human Genome Diversity Panel populations were used to further evaluate a 93 SNP AIM panel, a subset of the 128 AIMS set, for distinguishing continental origins. Using both model-based and relatively model-independent…
Genetic distance between populations
Posted by Razib Khan on May 5, 2009 In the comments below on the post on human population structure there was some request for a bigger global perspective. Below the fold I’ve placed a table with FST values which compare each population to the other. This an older population genetic statistic derived from the work of Sewall Wright, but you are almost certainly…
Human population structure, part n
Posted by Razib Khan on May 3, 2009 I still remember when L. L. Cavalli-Sforza’s The History and Geography of Human Genes was a candle in the dark, illuminating human history with slivers of genetic data laboriously gathered and analyzed over decades. We’ve come a long way. Dienekes points me to a new paper, Fine-scaled human genetic structure revealed by SNP microarrays: We…
One New World population expansion
Posted by Razib Khan on April 29, 2009 Haplotypic Background of a Private Allele at High Frequency in the Americas: Recently, the observation of a high-frequency private allele, the 9-repeat allele at microsatellite D9S1120, in all sampled Native American and Western Beringian populations has been interpreted as evidence that all modern Native Americans descend primarily from a single founding population. However, this inference…
The genetic architecture of different populations
Posted by Razib Khan on April 28, 2009 Dan MacArthur has a post, Genetics of complex traits in Europeans and East Asians: similarities and differences: With those goals in mind, you can expect to see many more GWAS of non-European populations over the next couple of years, and some explicit comparisons of the differing genetic architecture of complex traits between populations. Exciting times…
Genetic closeness != behavioral closeness
Posted by Razib Khan on February 20, 2009 Sheril’s post, Chimpanzees Are NOT Pets!, is good. She notes: 1 Chimpanzees are wild animals. Animals that make good PETS like dogs and cats, have been domesticated for [thousands] of years. There has been selection on them against aggression, which is why a dog, unlike a wolf, will not automatically tear you to pieces. Anyone…